Literature DB >> 24630285

Kleine-Levin syndrome: a case report and review of literature.

Sourav Das1, Ravi Gupta2, Mohan Dhyani1, Shailendra Raghuvanshi3.   

Abstract

BACKGROUND: Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently.
METHOD: We report a male adolescent who presented with recurrent hypersomnia, hypersexuality, and hyperorality. Magnetic resonance imaging of the brain and overnight polysomnography followed by a multiple sleep latency tests were ordered. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale.
RESULTS: Magnetic resonance imaging of the brain did not reveal any abnormality. Overnight video-synchronized polysomnography and multiple sleep latency tests ruled out narcolepsy. Epworth Sleepiness Scale score at baseline was 22. He was prescribed lithium carbonate 300 mg twice a day. The symptoms improved within a week after starting lithium carbonate therapy.
CONCLUSION: Kleine-Levin syndrome may present with hyperorality, and our patient responded well to lithium carbonate therapy.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Kleine-Levin syndrome; adolescent; lithium; recurrent hypersomnia

Mesh:

Substances:

Year:  2014        PMID: 24630285     DOI: 10.1016/j.pediatrneurol.2014.01.003

Source DB:  PubMed          Journal:  Pediatr Neurol        ISSN: 0887-8994            Impact factor:   3.372


  6 in total

1.  General Anesthetic Management of a Patient With Kleine-Levin Syndrome.

Authors:  Masatoshi Fujita; Kentaro Mizuta
Journal:  Anesth Prog       Date:  2022-04-01

2.  The Kleine-Levin Syndrome: A Rare Disease with Often Delayed Diagnosis-A Report of Two Cases in the Department of Neurology of the University Hospital of Cocody (Côte d'Ivoire).

Authors:  Berthe Assi; Constance Yapo-Ehounoud; Mohamed Ben Allaoui Baby; Evelyne Aka-Diarra; Muriel Amon-Tanoh; Christian Tanoh
Journal:  Case Rep Neurol Med       Date:  2016-02-17

3.  Recurrent hypersomnia: Report of medication-responsive cases.

Authors:  Bruna V Perin; Iorrana Rodrigues; Franciele T B Giasson; Matheus Balen; Naiana Posenato; Cassiano M Forcelini
Journal:  Sleep Sci       Date:  2015-06-29

Review 4.  Kleine-Levin syndrome: clues to aetiology.

Authors:  Saad Mohammed AlShareef; Richard Mark Smith; Ahmed Salem BaHammam
Journal:  Sleep Breath       Date:  2018-03-12       Impact factor: 2.816

5.  Kleine-Levin Syndrome in an 8-Year-Old Girl with Autistic Disorder: Does Autism Account a Primary or Secondary Cause?

Authors:  Mitra Hakim Shoushtari; Mirfarhad Ghalebandi; Azita Tavasoli; Maryam Pourshams
Journal:  Iran J Child Neurol       Date:  2015

6.  A Polysomnography Study of Kleine-Levin Syndrome in a Single Center.

Authors:  Yan-Wen Luo; Huan Yu; Lu-Hua Yuan; Guo-Xing Zhu
Journal:  Chin Med J (Engl)       Date:  2016-07-05       Impact factor: 2.628

  6 in total

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