Literature DB >> 24629519

Experimental and computational studies on the femoral fracture risk for advanced core decompression.

T N Tran1, S Warwas2, M Haversath2, T Classen2, H P Hohn3, M Jäger2, W Kowalczyk4, S Landgraeber5.   

Abstract

BACKGROUND: Two questions are often addressed by orthopedists relating to core decompression procedure: 1) Is the core decompression procedure associated with a considerable lack of structural support of the bone? and 2) Is there an optimal region for the surgical entrance point for which the fracture risk would be lowest? As bioresorbable bone substitutes become more and more common and core decompression has been described in combination with them, the current study takes this into account.
METHODS: Finite element model of a femur treated by core decompression with bone substitute was simulated and analyzed. In-vitro compression testing of femora was used to confirm finite element results.
FINDINGS: The results showed that for core decompression with standard drilling in combination with artificial bone substitute refilling, daily activities (normal walking and walking downstairs) are not risky for femoral fracture. The femoral fracture risk increased successively when the entrance point is located further distal. The critical value of the deviation of the entrance point to a more distal part is about 20mm.
INTERPRETATION: The study findings demonstrate that optimal entrance point should locate on the proximal subtrochanteric region in order to reduce the subtrochanteric fracture risk. Furthermore the consistent results of finite element and in-vitro testing imply that the simulations are sufficient.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Compression testing; Core decompression; Femoral fracture risk; Femoral head necrosis; Finite element simulation; Surgical entrance point

Mesh:

Substances:

Year:  2014        PMID: 24629519     DOI: 10.1016/j.clinbiomech.2014.02.001

Source DB:  PubMed          Journal:  Clin Biomech (Bristol, Avon)        ISSN: 0268-0033            Impact factor:   2.063


  7 in total

1.  Vascular endothelial growth factor/bone morphogenetic protein-2 bone marrow combined modification of the mesenchymal stem cells to repair the avascular necrosis of the femoral head.

Authors:  Xiao-Wei Ma; Da-Ping Cui; De-Wei Zhao
Journal:  Int J Clin Exp Med       Date:  2015-09-15

2.  Impact of Femoral Neck Cortical Bone Defect Induced by Core Decompression on Postoperative Stability: A Finite Element Analysis.

Authors:  Daizhu Yuan; Zhanyu Wu; Siwei Luo; Qiang Zou; Zihao Zou; Chuan Ye
Journal:  Biomed Res Int       Date:  2022-05-20       Impact factor: 3.246

3.  Core decompression versus other joint preserving treatments for osteonecrosis of the femoral head: a meta-analysis.

Authors:  Francesco Sadile; Alessio Bernasconi; Sergio Russo; Nicola Maffulli
Journal:  Br Med Bull       Date:  2016-06       Impact factor: 4.291

4.  Augmentation of core decompression with synthetic bone graft does not improve mechanical properties of the proximal femur.

Authors:  Samuel A Hockett; John T Sherrill; Micah Self; Simon C Mears; C Lowry Barnes; Erin M Mannen
Journal:  J Mech Behav Biomed Mater       Date:  2020-12-11

5.  Significance of Lateral Pillar in Osteonecrosis of Femoral Head: A Finite Element Analysis.

Authors:  Peng-Fei Wen; Wan-Shou Guo; Qi-Dong Zhang; Fu-Qiang Gao; Ju-An Yue; Zhao-Hui Liu; Li-Ming Cheng; Zi-Rong Li
Journal:  Chin Med J (Engl)       Date:  2017-11-05       Impact factor: 2.628

6.  In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium-based implant confers immediate biomechanical integrity.

Authors:  John D Stroncek; Jonathan L Shaul; Dominique Favell; Ronald S Hill; Bryan M Huber; James G Howe; Mary L Bouxsein
Journal:  J Orthop Res       Date:  2019-03-20       Impact factor: 3.494

7.  The effects of necrotic lesion size and orientation of the femoral component on stress alterations in the proximal femur in hip resurfacing - a finite element simulation.

Authors:  Ching-Lung Tai; Yung-Chou Chen; Pang-Hsin Hsieh
Journal:  BMC Musculoskelet Disord       Date:  2014-08-05       Impact factor: 2.362

  7 in total

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