Literature DB >> 24629110

Improved access to histopathology using a digital system could increase the organ donor pool and improve allocation.

Desley A H Neil1, Ian S D Roberts, Christopher O C Bellamy, Stephen J Wigmore, James M Neuberger.   

Abstract

Improvements in digital slide scanners have reached a stage that digital whole slide images (WSIs) can be used for diagnostic purposes. A digital system for histopathology, analogous to the systems used in radiology, would allow the establishment of networks of subspecialist histopathologists to provide a regional, national or even international rota to support out of hours histopathology for emergency frozen sections, urgent paraffin sections and to generally improve efficiencies with the provision of histopathology services. Such a system would promote appropriate organ utilization by allowing rapid characterization of unexpected lesions in the donor to determine whether donation should occur and further characterization of the organ, such as the degree of fibrosis in the kidney or steatosis in the liver, to determine whether the organ should be used. If introduced across Europe, this would promote safe and effective exchange of organs and support a cost efficient use of pathologist expertise. This review article outlines current issues with the provision of an urgent out of hours histopathology service and focuses on how such a service has the potential to increase organ donors, improve allocation, sharing and the use of available donor organs.
© 2014 Steunstichting ESOT.

Entities:  

Keywords:  digital pathology; donor lesion; histopathology; organ allocation

Mesh:

Year:  2014        PMID: 24629110     DOI: 10.1111/tri.12320

Source DB:  PubMed          Journal:  Transpl Int        ISSN: 0934-0874            Impact factor:   3.782


  5 in total

Review 1.  Donor liver histology--a valuable tool in graft selection.

Authors:  Christa Flechtenmacher; Peter Schirmacher; Peter Schemmer
Journal:  Langenbecks Arch Surg       Date:  2015-03-26       Impact factor: 3.445

2.  Development of a Whole Slide Imaging System on Smartphones and Evaluation With Frozen Section Samples.

Authors:  Hong Yu; Feng Gao; Liren Jiang; Shuoxin Ma
Journal:  JMIR Mhealth Uhealth       Date:  2017-09-15       Impact factor: 4.773

Review 3.  The Landscape of Digital Pathology in Transplantation: From the Beginning to the Virtual E-Slide.

Authors:  Ilaria Girolami; Anil Parwani; Valeria Barresi; Stefano Marletta; Serena Ammendola; Lavinia Stefanizzi; Luca Novelli; Arrigo Capitanio; Matteo Brunelli; Liron Pantanowitz; Albino Eccher
Journal:  J Pathol Inform       Date:  2019-07-01

4.  Validation of Remote Digital Frozen Sections for Cancer and Transplant Intraoperative Services.

Authors:  Luca Cima; Matteo Brunelli; Anil Parwani; Ilaria Girolami; Andrea Ciangherotti; Giulio Riva; Luca Novelli; Francesca Vanzo; Alessandro Sorio; Vito Cirielli; Mattia Barbareschi; Antonietta D'Errico; Aldo Scarpa; Chiara Bovo; Filippo Fraggetta; Liron Pantanowitz; Albino Eccher
Journal:  J Pathol Inform       Date:  2018-10-09

5.  Innovation in Transplantation: The Digital Era.

Authors:  Albino Eccher; Matteo Brunelli; Liron Pantanowitz; Anil Parwani; Ilaria Girolami; Aldo Scarpa
Journal:  J Pathol Inform       Date:  2018-09-27
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.