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Literature DB >> 24629039

Ex-vivo lung perfusion.

Dirk Van Raemdonck^1,2, Arne Neyrinck^2,3, Marcelo Cypel^4,5, Shaf Keshavjee^4,5.

Abstract

This review outlines the new and promising technique of ex vivo lung perfusion and its clinical potential to increase the number of transplantable lungs and to improve the early and late outcome after transplantation. The rationale, the experimental background, the technique and protocols, and available devices for ex vivo lung perfusion are discussed. The current clinical experience worldwide and ongoing clinical trials are reviewed.

Keywords: ex vivo lung perfusion; lung assessment; lung conditioning; lung preservation; lung repair; lung transplantation

Mesh：

Year: 2014 PMID： 24629039 DOI： 10.1111/tri.12317

Source DB: PubMed Journal: Transpl Int ISSN： 0934-0874 Impact factor: 3.782

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Cited

30 in total

Review 1. History of lung transplantation.

Authors: Federico Venuta; Dirk Van Raemdonck
Journal: J Thorac Dis Date: 2017-12 Impact factor: 2.895

Review 2. Ex vivo lung perfusion prior to transplantation: an overview of current clinical practice worldwide.

Authors: Julien Possoz; Arne Neyrinck; Dirk Van Raemdonck
Journal: J Thorac Dis Date: 2019-04 Impact factor: 2.895

3. Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death.

Authors: Matthew F Blum; Qiang Liu; Basem Soliman; Paul Dreher; Toshihiro Okamoto; Emilio D Poggio; David A Goldfarb; William M Baldwin; Cristiano Quintini
Journal: J Surg Res Date: 2017-04-20 Impact factor: 2.192

4. Ex vivo lung perfusion as a human platform for preclinical small molecule testing.

Authors: Nathaniel M Weathington; Diana Álvarez; John Sembrat; Josiah Radder; Nayra Cárdenes; Kentaro Noda; Qiaoke Gong; Hesper Wong; Jay Kolls; Jonathan D'Cunha; Rama K Mallampalli; Bill B Chen; Mauricio Rojas
Journal: JCI Insight Date: 2018-10-04

Review 5. The Future of Lung Transplantation.

Authors: Katherine A Young; Daniel F Dilling
Journal: Chest Date: 2018-08-29 Impact factor: 9.410

6. Stereological assessment of the blood-air barrier and the surfactant system after mesenchymal stem cell pretreatment in a porcine non-heart-beating donor model for lung transplantation.

Authors: Anke Schnapper; Astrid Christmann; Lars Knudsen; Parwis Rahmanian; Yeong-Hoon Choi; Mohamed Zeriouh; Samira Karavidic; Klaus Neef; Anja Sterner-Kock; Maria Guschlbauer; Florian Hofmaier; Alexandra C Maul; Thorsten Wittwer; Thorsten Wahlers; Christian Mühlfeld; Matthias Ochs
Journal: J Anat Date: 2017-11-28 Impact factor: 2.610

Ex-vivo lung perfusion.

Review 1. History of lung transplantation.

Review 2. Ex vivo lung perfusion prior to transplantation: an overview of current clinical practice worldwide.

3. Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death.

4. Ex vivo lung perfusion as a human platform for preclinical small molecule testing.

Review 5. The Future of Lung Transplantation.

6. Stereological assessment of the blood-air barrier and the surfactant system after mesenchymal stem cell pretreatment in a porcine non-heart-beating donor model for lung transplantation.

Review 7. Machine perfusion of thoracic organs.

Review 8. Optimizing organs for transplantation; advancements in perfusion and preservation methods.

9. Use of modified Custodiol-N as perfusion solution in ex vivo lung perfusion.

Review 10. Mixing old and young: enhancing rejuvenation and accelerating aging.