Literature DB >> 2462867

Vitronectin is phosphorylated by a cAMP-dependent protein kinase released by activation of human platelets with thrombin.

B Korc-Grodzicki1, M Tauber-Finkelstein, D Chain, S Shaltiel.   

Abstract

Activation of freshly isolated human platelets with a physiological stimulant (thrombin) causes them to release a cAMP-dependent protein kinase which specifically phosphorylates one plasma protein (Mr 75000). This protein is immunochemically and biochemically identified as vitronectin (also know as S protein), which was previously implicated in blood clotting, complement function and cell adhesion.

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Year:  1988        PMID： 2462867     DOI： 10.1016/s0006-291x(88)80991-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  10 in total

1.  Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which 'buries' Ser-378, its site of phosphorylation by protein kinase A.

Authors:  D Chain; B Korc-Grodzicki; T Kreizman; S Shaltiel
Journal:  Biochem J       Date:  1991-03-01       Impact factor: 3.857

Review 2.  Evidence for an extra-cellular function for protein kinase A.

Authors:  S Shaltiel; I Schvartz; B Korc-Grodzicki; T Kreizman
Journal:  Mol Cell Biochem       Date:  1993-11       Impact factor: 3.396

Review 3.  Extracellular Protein Phosphorylation, the Neglected Side of the Modification.

Authors:  Eva Klement; Katalin F Medzihradszky
Journal:  Mol Cell Proteomics       Date:  2016-11-10       Impact factor: 5.911

4.  The cluster of basic amino acids in vitronectin contributes to its binding of plasminogen activator inhibitor-1: evidence from thrombin-, elastase- and plasmin-cleaved vitronectins and anti-peptide antibodies.

Authors:  Z Gechtman; A Belleli; S Lechpammer; S Shaltiel
Journal:  Biochem J       Date:  1997-07-15       Impact factor: 3.857

Review 5.  The role of vitronectin as multifunctional regulator in the hemostatic and immune systems.

Authors:  K T Preissner
Journal:  Blut       Date:  1989-11

6.  Phosphorylation of complement factor C3 in vivo.

Authors:  S C Martin
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

7.  Low levels of serum vitronectin associated with clinical phases in patients with hemorrhagic fever with renal syndrome.

Authors:  Zhengwen Liu; Qunying Han; Lei Zhang; Qianzi Zhao; Jinghong Chen; Sai Lou
Journal:  Clin Exp Med       Date:  2009-05-01       Impact factor: 3.984

8.  Gelatin-Methacryloyl (GelMA) Formulated with Human Platelet Lysate Supports Mesenchymal Stem Cell Proliferation and Differentiation and Enhances the Hydrogel's Mechanical Properties.

Authors:  Marline Kirsch; Luise Birnstein; Iliyana Pepelanova; Wiebke Handke; Jessica Rach; Axel Seltsam; Thomas Scheper; Antonina Lavrentieva
Journal:  Bioengineering (Basel)       Date:  2019-08-28

Review 9.  The Human Platelet as an Innate Immune Cell: Interactions Between Activated Platelets and the Complement System.

Authors:  Oskar Eriksson; Camilla Mohlin; Bo Nilsson; Kristina N Ekdahl
Journal:  Front Immunol       Date:  2019-07-10       Impact factor: 7.561

10.  The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.

Authors:  Leila Revollo; Glenn Merrill-Skoloff; Karen De Ceunynck; James R Dilks; Shihui Guo; Mattia R Bordoli; Christian G Peters; Leila Noetzli; Andreia Ionescu; Vicki Rosen; Joseph E Italiano; Malcolm Whitman; Robert Flaumenhaft
Journal:  Blood       Date:  2022-01-06       Impact factor: 25.476
  10 in total

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