Kıvılcım Gören1, Nevin Sağsöz2, Volkan Noyan2, Aykan Yücel2, Osman Cağlayan3, Mehmet Sühha Bostancı4. 1. Department of Gynecology and Obstetrics, Haci Hidayet Dogruer State Hospital, Specialist of Obstetric and Gynecology, Kırıkkale, Turkey. 2. Department of Gynecology and Obstetrics, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey. 3. Department of Biochemistry, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey. 4. Specialist of Obstetric and Gynecology, Sakarya Education and Research Hospital, Sakarya, Turkey.
Abstract
OBJECTIVE: The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls. MATERIAL AND METHODS: Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked. RESULTS: Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group. CONCLUSION: Plasma apelin levels were significantly higher in PCOS patients.
OBJECTIVE: The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls. MATERIAL AND METHODS: Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked. RESULTS: Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group. CONCLUSION: Plasma apelin levels were significantly higher in PCOSpatients.
Entities:
Keywords:
Apelin; Ferriman Gallwey score (FGS); Homeostatic Model Assessment insulin resistance (HOMA-IR); polycystic ovary syndrome; waist to hip ratio
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