Literature DB >> 24627604

Forward-viewing radial-array echoendoscope for staging of colon cancer beyond the rectum.

Pradermchai Kongkam1, Sittikorn Linlawan1, Satimai Aniwan1, Narisorn Lakananurak1, Suparat Khemnark1, Chucheep Sahakitrungruang1, Jirawat Pattanaarun1, Supakij Khomvilai1, Naruemon Wisedopas1, Wiriyaporn Ridtitid1, Manoop S Bhutani1, Pinit Kullavanijaya1, Rungsun Rerknimitr1.   

Abstract

AIM: To evaluate feasibility of the novel forward-viewing radial-array echoendoscope for staging of colon cancer beyond rectum as the first series.
METHODS: A retrospective study with prospectively entered database. From March 2012 to February 2013, a total of 21 patients (11 men) (mean age 64.2 years) with colon cancer beyond the rectum were recruited. The novel forward-viewing radial-array echoendoscope was used for ultrasonographic staging of colon cancer beyond rectum. Ultrasonographic T and N staging were recorded when surgical pathology was used as a gold standard.
RESULTS: The mean time to reach the lesion and the mean time to complete the procedure were 3.5 and 7.1 min, respectively. The echoendoscope passed through the lesions in 13 patients (61.9%) and reached the cecum in 10 of 13 patients (76.9%). No adverse events were found. The lesions were located in the cecum (n = 2), ascending colon (n = 1), transverse colon (n = 2), descending colon (n = 2), and sigmoid colon (n = 14). The accuracy rate for T1 (n = 3), T2 (n = 4), T3 (n = 13) and T4 (n = 1) were 100%, 60.0%, 84.6% and 100%, respectively. The overall accuracy rates for the T and N staging of colon cancer were 81.0% and 52.4%, respectively. The accuracy rates among traversable lesions (n = 13) and obstructive lesions (n = 8) were 61.5% and 100%, respectively. Endoscopic ultrasound and computed tomography had overall accuracy rates of 81.0% and 68.4%, respectively.
CONCLUSION: The echoendoscope is a feasible staging tool for colon cancer beyond rectum. However, accuracy of the echoendoscope needs to be verified by larger systematic studies.

Entities:  

Keywords:  Colon; Colon cancer; Colonoscopy; Endoscopic ultrasound; Forward-viewing; Neoadjuvan therapy; Neoplasm; Staging

Mesh:

Year:  2014        PMID: 24627604      PMCID: PMC3949277          DOI: 10.3748/wjg.v20.i10.2681

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


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