Literature DB >> 24627165

STEAP4 and insulin resistance.

Xiaoling Chen1, Zhiqing Huang, Bo Zhou, Huan Wang, Gang Jia, Guangmang Liu, Hua Zhao.   

Abstract

Obesity is a multifactorial disease that caused by the interactions between genetic susceptibility genes and environmental cues. Obesity is considered as a major risk factor of insulin resistance. STEAP4 is a novel anti-obesity gene that is significantly down-regulated in adipose tissue of obese patients. Over-expression of STEAP4 can improve glucose uptake and mitochondrial function, and increase insulin sensitivity. STEAP4 expression is regulated by a variety of inflammatory cytokines, hormones, or adipokines. In this review, we discuss function of STEAP4 in regulating insulin resistance in adipose tissue in vivo, as well as in adipocytes in vitro.

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Year:  2014        PMID： 24627165     DOI： 10.1007/s12020-014-0230-1

Source DB:  PubMed          Journal:  Endocrine        ISSN： 1355-008X            Impact factor:   3.633


  95 in total

Review 1.  The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins.

Authors:  R Lill; K Diekert; A Kaut; H Lange; W Pelzer; C Prohl; G Kispal
Journal:  Biol Chem       Date:  1999-10       Impact factor: 3.915

2.  Six-transmembrane epithelial antigen of prostate 4 (STEAP4) is expressed on monocytes/neutrophils, and is regulated by TNF antagonist in patients with rheumatoid arthritis.

Authors:  Y Tanaka; I Matsumoto; K Iwanami; A Inoue; N Umeda; Y Tanaka; M Sugihara; T Hayashi; S Ito; T Sumida
Journal:  Clin Exp Rheumatol       Date:  2012-03-06       Impact factor: 4.473

3.  Greater prevalence of iron deficiency in overweight and obese children and adolescents.

Authors:  O Pinhas-Hamiel; R S Newfield; I Koren; Arnon Agmon; P Lilos; M Phillip
Journal:  Int J Obes Relat Metab Disord       Date:  2003-03

4.  Association of the six transmembrane protein of prostate 2 gene polymorphisms with metabolic syndrome in Han Chinese population.

Authors:  Wenchao Zhang; Mengxiong Tang; Ming Zhong; Zhihao Wang; Yuanyuan Shang; Huiping Gong; Yun Zhang; Wei Zhang
Journal:  Diabetes Metab Syndr       Date:  2013-07-23

5.  Inflammation and iron deficiency in the hypoferremia of obesity.

Authors:  L B Yanoff; C M Menzie; B Denkinger; N G Sebring; T McHugh; A T Remaley; J A Yanovski
Journal:  Int J Obes (Lond)       Date:  2007-04-17       Impact factor: 5.095

Review 6.  Insulin receptor signals regulating GLUT4 translocation and actin dynamics.

Authors:  Makoto Kanzaki
Journal:  Endocr J       Date:  2006-05-12       Impact factor: 2.349

7.  STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.

Authors:  Xiaohui Chen; Chun Zhu; Chenbo Ji; Yaping Zhao; Chunmei Zhang; Fukun Chen; Chunlin Gao; Jingai Zhu; Lingmei Qian; Xirong Guo
Journal:  Int J Mol Med       Date:  2010-03       Impact factor: 4.101

8.  Downregulation of STEAP4, a highly-expressed TNF-alpha-inducible gene in adipose tissue, is associated with obesity in humans.

Authors:  Chun-Mei Zhang; Xia Chi; Bin Wang; Min Zhang; Yu-Hui Ni; Rong-Hua Chen; Xiao-Nan Li; Xi-Rong Guo
Journal:  Acta Pharmacol Sin       Date:  2008-05       Impact factor: 6.150

9.  Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.

Authors:  Stephan Glund; Atul Deshmukh; Yun Chau Long; Theodore Moller; Heikki A Koistinen; Kenneth Caidahl; Juleen R Zierath; Anna Krook
Journal:  Diabetes       Date:  2007-03-15       Impact factor: 9.461

10.  [The role of TNFalpha-induced adipose-related protein (TIARP) in TNFalpha dependent arthritic model--GPI-induced arthritis].

Authors:  Asuka Inoue; Isao Matsumoto; Keiichi Iwanami; Yoko Tanaka; Takayuki Sumida
Journal:  Nihon Rinsho Meneki Gakkai Kaishi       Date:  2009-02
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  7 in total

1.  STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

Authors:  Hannah M Gordon; Neil Majithia; Patrick E MacDonald; Jocelyn E Manning Fox; Poonam R Sharma; Frances L Byrne; Kyle L Hoehn; Carmella Evans-Molina; Linda Langman; Kenneth L Brayman; Craig S Nunemaker
Journal:  Endocrine       Date:  2017-04-12       Impact factor: 3.633

2.  Genetic Variants in Six-Transmembrane Epithelial Antigen of Prostate 4 Increase Risk of Developing Metabolic Syndrome in a Han Chinese Population.

Authors:  Yue Qi; Yaqin Yu; Yanhua Wu; Shibin Wang; Qiong Yu; Jieping Shi; Ziqi Xu; Qingqing Zhang; Yingli Fu; Yao Fu; Changgui Kou
Journal:  Genet Test Mol Biomarkers       Date:  2015-10-28

Review 3.  STEAP4: its emerging role in metabolism and homeostasis of cellular iron and copper.

Authors:  Rachel T Scarl; C Martin Lawrence; Hannah M Gordon; Craig S Nunemaker
Journal:  J Endocrinol       Date:  2017-06-02       Impact factor: 4.286

4.  Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation.

Authors:  Wei Zhao; Qiang Xu; Jiahui Yang; Xianghong Xie; Chunmei Li; Weihong Zhang; Enhui Chen; Yanfang Guo; Mingyue Gao; Jie Shi; Huabing Zhang; Hong Yao; Meixia Li; Li Yan; Fude Fang; Wenming Wu; Xiaojun Liu
Journal:  iScience       Date:  2022-06-07

5.  STEAP4 Inhibits HIF-1α/PKM2 Signaling and Reduces High Glucose-Induced Apoptosis of Retinal Vascular Endothelial Cells.

Authors:  Lei Liu; Hui Xu; Hongyu Zhao; Chunying Jiang
Journal:  Diabetes Metab Syndr Obes       Date:  2020-07-20       Impact factor: 3.168

6.  Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.

Authors:  Ting Luo; Xianli Zeng; Wenqi Yang; Yuelan Zhang
Journal:  Anatol J Cardiol       Date:  2019-04       Impact factor: 1.596

7.  In silico analysis of expression data during the early priming stage of liver regeneration after partial hepatectomy in rat.

Authors:  Li Yin; Xueqiang Guo; Chunyan Zhang; Zhihui Cai; Cunshuan Xu
Journal:  Oncotarget       Date:  2018-01-27
  7 in total

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