João Florêncio de Abreu Baptista1, Renato Santiago Gomez2, Danilo Nagib Salomão Paulo3, Antonio Roberto Carraretto4, Marcos Celio Brocco5, José Jorge Silva6. 1. Espirito Santo Federal University, Department of Surgical Clinic, VitoriaES, Brazil, Master, Fellow PhD degree, Postgraduate Program in Ophthalmological Surgical and Applied Sciences, Minas Gerais Federal University (UFMG). Associate professor, Division of Anesthesiology, Department of Surgical Clinic, Espirito Santo Federal University (UFES), Vitoria-ES, Brazil. Conception, design and scientific content of the study. 2. UFMG, Department of Surgery, Minas Gerais, Brazil, Associate Professor, Division of Anesthesiology, Department of Surgery, UFMG, Minas Gerais, Brazil. Conception and scientific content of the study. 3. EMESCAM, College of Health Sciences, Department of Surgery, VitoriaES, Brazil, Full Professor, Department of Surgery, College of Health Sciences, EMESCAM, Vitoria-ES, Brazil. Critical revision. 4. Espirito Santo Federal University, Department of Surgery, VitoriaES, Brazil, IVPhD, Associate Professor, Division of Anesthesiology, Department of Surgery, Espirito Santo Federal University (UFES), Vitoria-ES, Brazil. Manuscript writing, critical revision. 5. UFES, Department of Surgical Clinic, VitoriaES, Brazil, VPhD, Associate Professor, Division of Anesthesiology, Department of Surgical Clinic, UFES, Vitoria-ES, Brazil. Statistical analysis, critical revision. 6. UFES, Department of Surgical, VitoriaES, Brazil, Master, Assistant Professor, Division of Surgery, Department of Surgery, UFES, Vitoria-ES Brazil. Statistical analysis, critical revision.
Abstract
PURPOSE: To determine the safety, pain intensity correlated with age and body mass index (BMI), epidural anesthesia with ropivacaine and clonidine in hemorrhoidectomy. METHODS:Eighty patients, both genders, 20-70 years old, ASA I or II, for hemorrhoidectomy were randomly divided into two groups: Control (n=38), epidural anesthesia with 14 mL of ropivacaine 0.75 % plus 0.0266 mL/kg of 0.9% saline solution; Experimental (n=42) epidural anesthesia with 14 mL of 0.75% ropivacaine plus 4.0 mcg/kg of clonidine. In preoperative and postoperative period were evaluated: systolic blood pressure (SBP), diastolic blood pressure (DBP ), heart rate (HR ), pulse oximetry (SpO2), electrocardiography (ECG), pain intensity (VAS ) in four, eight and, 12 hours and analgesic consumption. RESULTS: The VAS values differed between four, eight and 12 hours in the Experimental Group, where correlation of VAS 12h with age (p<0.05) occurred and not with BMI and more patients (p<0.05) did not receive analgesics. SBP, DBP, HR changed similarly in both groups at 15, 30 and 45 min. The ECG and SpO2 remained unchanged. CONCLUSIONS:Clonidine (4mcg/kg) in epidural anesthesia with ropivacaine 0.75% in hemorrhoidectomy showed safety and greater analgesia within four hours. The pain at 12 hours showed correlation with age and not with body mass index.
RCT Entities:
PURPOSE: To determine the safety, pain intensity correlated with age and body mass index (BMI), epidural anesthesia with ropivacaine and clonidine in hemorrhoidectomy. METHODS: Eighty patients, both genders, 20-70 years old, ASA I or II, for hemorrhoidectomy were randomly divided into two groups: Control (n=38), epidural anesthesia with 14 mL of ropivacaine 0.75 % plus 0.0266 mL/kg of 0.9% saline solution; Experimental (n=42) epidural anesthesia with 14 mL of 0.75% ropivacaine plus 4.0 mcg/kg of clonidine. In preoperative and postoperative period were evaluated: systolic blood pressure (SBP), diastolic blood pressure (DBP ), heart rate (HR ), pulse oximetry (SpO2), electrocardiography (ECG), pain intensity (VAS ) in four, eight and, 12 hours and analgesic consumption. RESULTS: The VAS values differed between four, eight and 12 hours in the Experimental Group, where correlation of VAS 12h with age (p<0.05) occurred and not with BMI and more patients (p<0.05) did not receive analgesics. SBP, DBP, HR changed similarly in both groups at 15, 30 and 45 min. The ECG and SpO2 remained unchanged. CONCLUSIONS:Clonidine (4mcg/kg) in epidural anesthesia with ropivacaine 0.75% in hemorrhoidectomy showed safety and greater analgesia within four hours. The pain at 12 hours showed correlation with age and not with body mass index.
Authors: Anoushka M Afonso; Martin I Newman; Neil Seeley; Jacob Hutchins; Kevin L Smith; Gabriel Mena; Jesse C Selber; Michel H Saint-Cyr; Jeffrey C Gadsden Journal: Plast Reconstr Surg Glob Open Date: 2017-09-15
Authors: Shahbaz Alam; B Pramod Krishna; Santosh Kumaran; S Manu Prasad; M A Lakshith Biddappa; T M Kalappa; S Gowtham; N Anees Ahmed Journal: Ann Maxillofac Surg Date: 2019 Jul-Dec