Literature DB >> 2462565

Chemotherapy in head and neck cancer with bleomycin, cisplatinum, and methotrexate.

T Deitmer1, D Urbanitz.   

Abstract

Results of chemotherapy in head and neck cancers are reported with a regimen of cisplatinum, bleomycin and methotrexate. In 63 previously untreated patients, the overall response rate was 73%, including 13/63 CR and 33/63 PR. The response rate in 20 previously treated tumors was 20%. The chemotherapy protocol was well tolerated without severe complications. Initial chemotherapy as a third modality in addition to radiotherapy and/or surgery is discussed.

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Year:  1988        PMID: 2462565     DOI: 10.1007/bf00398192

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  13 in total

1.  [Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].

Authors:  M Schröder; H W von Heyden; A Scherpe; G A Nagel
Journal:  Laryngol Rhinol Otol (Stuttg)       Date:  1986-01

2.  [Induction chemotherapy in cancers of the respiratory and digestive tracts by continuous infusions combining cisplatinum (C), fluorouracil (F), bleomycin (B) or C and F].

Authors:  V Bassot; D Brasnu; J Lacau-St-Guily; A Fabre; M Menard; S Donnadieu; C Jacquillat; H Laccourreye
Journal:  Ann Otolaryngol Chir Cervicofac       Date:  1986

3.  [Induction chemotherapy in cancer of the upper respiratory and digestive tract. Preliminary results of the protocol combining cisplatin, 5-fluorouracil and bleomycin (CFB)].

Authors:  H Laccourreye; V Bassot; J Lacau St Guily; D Brasnu; M Menard; S Donnadieu; C Jacquillat
Journal:  Ann Otolaryngol Chir Cervicofac       Date:  1985

4.  Combined modality approach in the management of locally advanced head and neck cancer.

Authors:  C T Coughlin; M Grace; J F O'Donnell; P J LeMarbre; W D Morain; N A Geurkink; O R McIntyre
Journal:  Cancer Treat Rep       Date:  1984-04

5.  A prospective evaluation of 5-fluorouracil plus cisplatin in advanced squamous-cell cancer of the head and neck.

Authors:  K S Dasmahapatra; P Citrin; G J Hill; R Yee; M A Mohit-Tabatabai; B F Rush
Journal:  J Clin Oncol       Date:  1985-11       Impact factor: 44.544

6.  A randomized trial of cisplatin (CACP) + 5-fluorouracil (5-FU) infusion and CACP + 5-FU bolus for recurrent and advanced squamous cell carcinoma of the head and neck.

Authors:  J A Kish; J F Ensley; J Jacobs; A Weaver; G Cummings; M Al-Sarraf
Journal:  Cancer       Date:  1985-12-15       Impact factor: 6.860

7.  Treatment of squamous-cell carcinoma of the head and neck with cisplatin and 5-fluorouracil.

Authors:  P C Amrein; S A Weitzman
Journal:  J Clin Oncol       Date:  1985-12       Impact factor: 44.544

8.  [Cytostatic primary therapy of squamous cell carcinoma of the oro- and hypopharynx with cisplatin, bleomycin and methotrexate].

Authors:  T Deitmer; D Urbanitz
Journal:  Laryngol Rhinol Otol (Stuttg)       Date:  1986-01

9.  A randomized trial of the combination of cis-platinum, oncovin and bleomycin (COB) versus methotrexate in patients with advanced squamous cell carcinoma of the head and neck.

Authors:  A Drelichman; G Cummings; M Al-Sarraf
Journal:  Cancer       Date:  1983-08-01       Impact factor: 6.860

10.  Advanced squamous carcinoma of the head and neck. A preliminary report of neoadjuvant chemotherapy with cisplatin, bleomycin, and methotrexate.

Authors:  T J Ervin; R R Weichselbaum; R L Fabian; D Miller; C M Norris; M R Posner; C Rose; P Lockhart; S A Tuttle; J M MacIntyre
Journal:  Arch Otolaryngol       Date:  1984-04
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