Literature DB >> 2462508

Demonstration of immunochemical identity between the synaptic vesicle proteins synaptin and synaptophysin/p38.

H Gaardsvoll1, D Obendorf, H Winkler, E Bock.   

Abstract

The synaptic vesicle proteins synaptin and synaptophysin/p38 were shown to be immunochemically identical. Western immunoblot analysis of Triton X-100 extracts from rat brain showed that polyclonal polyspecific anti-synaptin antibodies and monoclonal antibody SY38 against synaptophysin both reacted with a band of 38 kDa. In two-dimensional immunoblots of chromaffin granule membranes from bovine adrenal medulla anti-synaptin and anti-synaptophysin antibodies also recognized the same component. Finally, in a Western immunoblotting experiment SY38 reacted with an immuno-isolated synaptin antigen.

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Year:  1988        PMID: 2462508     DOI: 10.1016/0014-5793(88)80997-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  6 in total

Review 1.  Membrane composition of adrenergic large and small dense cored vesicles and of synaptic vesicles: consequences for their biogenesis.

Authors:  H Winkler
Journal:  Neurochem Res       Date:  1997-08       Impact factor: 3.996

2.  Special issue dedicated to Elisabeth Bock.

Authors:  Vladimir Berezin
Journal:  Neurochem Res       Date:  2013-06       Impact factor: 3.996

3.  Synaptic proteins are tonotopically graded in postnatal and adult type I and type II spiral ganglion neurons.

Authors:  Jacqueline Flores-Otero; Robin L Davis
Journal:  J Comp Neurol       Date:  2011-06-01       Impact factor: 3.215

4.  Svp25, a synaptic vesicle membrane glycoprotein from Torpedo electric organ that binds calcium and forms a homo-oligomeric complex.

Authors:  W Volknandt; M Schläfer; F Bonzelius; H Zimmermann
Journal:  EMBO J       Date:  1990-08       Impact factor: 11.598

Review 5.  Neural cell adhesion molecule (NCAM) as a quantitative marker in synaptic remodeling.

Authors:  O S Jørgensen
Journal:  Neurochem Res       Date:  1995-05       Impact factor: 3.996

6.  Organ of Corti explants direct tonotopically graded morphology of spiral ganglion neurons in vitro.

Authors:  Felicia L Smith; Robin L Davis
Journal:  J Comp Neurol       Date:  2015-12-25       Impact factor: 3.215

  6 in total

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