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Literature DB >> 24624326

Cryptococcal rib osteomyelitis as primary and only symptom of idiopathic CD4 penia.

Rebecca A Legarth¹, Merete Christensen², Henrik Calum³, Terese L Katzenstein¹, Jannik Helweg-Larsen¹.

Abstract

A 59-year old man with idiopathic CD4 lymphopenia presented with extensive disseminated Cryptococcus neoformans infection including a large rib cryptoccocoma, vertebral spondylitis and pleural empyema. Complete resection of the affected part of the rib was necessary after failure of initial antifungal treatment. The vertebral spondylitis has been successfully managed at 3 years of follow-up by continuous itraconazole treatment and regular MRI combined with leucocyte scintigraphy assessment.

Entities: Chemical Disease Gene Species

Keywords: C. neoformans; Cryptococcoma; Idiopathic CD4 penia; Spondylitis

Year: 2014 PMID： 24624326 PMCID： PMC3950534 DOI： 10.1016/j.mmcr.2014.02.002

Source DB: PubMed Journal: Med Mycol Case Rep ISSN： 2211-7539

20 in total

1. The changing epidemiology of cryptococcosis: an update from population-based active surveillance in 2 large metropolitan areas, 1992-2000.

Authors: Sara A Mirza; Maureen Phelan; David Rimland; Edward Graviss; Richard Hamill; Mary E Brandt; Tracie Gardner; Matthew Sattah; Gabriel Ponce de Leon; Wendy Baughman; Rana A Hajjeh
Journal: Clin Infect Dis Date: 2003-02-27 Impact factor: 9.079

Review 2. Cryptococcosis.

Authors: Methee Chayakulkeeree; John R Perfect
Journal: Infect Dis Clin North Am Date: 2006-09 Impact factor: 5.982

Review 3. Host defenses against cryptococcosis.

Authors: Michael S Price; John R Perfect
Journal: Immunol Invest Date: 2011 Impact factor: 3.657

Review 4. Osteomyelitis of the ribs in the antibiotic era.

Authors: J Bishara; D Gartman-Israel; M Weinberger; S Maimon; G Tamir; S Pitlik
Journal: Scand J Infect Dis Date: 2000

5. Diagnostic and therapeutic management of lumbar and thoracic spondylodiscitis--an evaluation of 59 cases.

Authors: D C Wirtz; I Genius; J E Wildberger; G Adam; K W Zilkens; F U Niethard
Journal: Arch Orthop Trauma Surg Date: 2000 Impact factor: 3.067

Review 6. Cryptococcal osteomyelitis: case report and review.

Authors: P Y Liu
Journal: Diagn Microbiol Infect Dis Date: 1998-01 Impact factor: 2.803

7. Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy.

Authors: P G Pappas; J R Perfect; G A Cloud; R A Larsen; G A Pankey; D J Lancaster; H Henderson; C A Kauffman; D W Haas; M Saccente; R J Hamill; M S Holloway; R M Warren; W E Dismukes
Journal: Clin Infect Dis Date: 2001-07-26 Impact factor: 9.079

Review 8. Cryptococcal skeletal infections: case report and review.

Authors: R E Behrman; J R Masci; P Nicholas
Journal: Rev Infect Dis Date: 1990 Mar-Apr

9. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

Authors: John R Perfect; William E Dismukes; Francoise Dromer; David L Goldman; John R Graybill; Richard J Hamill; Thomas S Harrison; Robert A Larsen; Olivier Lortholary; Minh-Hong Nguyen; Peter G Pappas; William G Powderly; Nina Singh; Jack D Sobel; Tania C Sorrell
Journal: Clin Infect Dis Date: 2010-02-01 Impact factor: 9.079

Cryptococcal rib osteomyelitis as primary and only symptom of idiopathic CD4 penia.

1. The changing epidemiology of cryptococcosis: an update from population-based active surveillance in 2 large metropolitan areas, 1992-2000.

Review 2. Cryptococcosis.

Review 3. Host defenses against cryptococcosis.

Review 4. Osteomyelitis of the ribs in the antibiotic era.

5. Diagnostic and therapeutic management of lumbar and thoracic spondylodiscitis--an evaluation of 59 cases.

Review 6. Cryptococcal osteomyelitis: case report and review.

7. Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy.

Review 8. Cryptococcal skeletal infections: case report and review.

9. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

Review 10. Idiopathic CD4 lymphocytopenia: a case of missing, wandering or ineffective T cells.

1. Idiopathic CD4 lymphocytopenia: Pathogenesis, etiologies, clinical presentations and treatment strategies.

2. Cryptococcal spondylodiscitis in a non-HIV patient with CD4 lymphocytopenia.

Review 3. Thoracolumbar Scoliosis Due to Cryptococcal Osteomyelitis: A Case Report and Review of the Literature.

Review 4. Idiopathic CD4 Lymphocytopenia: Current Insights.