Literature DB >> 24623869

Pharmacy management of postoperative blood glucose in open heart surgery patients: evaluation of an intravenous to subcutaneous insulin protocol.

Amanda Stahnke1, Kelly Struemph2, Erin Behnen3, Julia Schimmelpfennig4.   

Abstract

PURPOSE: To develop and implement a protocol to improve blood glucose (BG) control during transition from intravenous (IV) to subcutaneous (SC) insulin, increase compliance with Surgical Care Improvement Project (SCIP) measures, and decrease sternal wound infections post open heart surgery (OHS).
METHODS: An IV to SC protocol was developed and implemented. A retrospective chart review of patients who underwent OHS was conducted from January 2, 2009 to September 30, 2010 (pre protocol) and from October 1, 2010 to December 31, 2011 (post protocol). Data collected included age, sex, history of diabetes mellitus (DM), BG values, hypoglycemia incidence, length of stay, and incidence of sternal wound infections.
RESULTS: A total of 243 patients were included in the study. Compliance with SCIP postoperative day 1 and 2 BG goals was similar pre and post protocol (P = .24 and .248). One sternal wound infection occurred after protocol implementation, whereas 6 occurred pre protocol (P = .046). Change in BG when transitioning from IV to SC insulin was similar between the groups, however there were significantly fewer hypoglycemia episodes post protocol (P < .001).
CONCLUSION: Though differences were not found in compliance with SCIP postoperative day 1 and 2 measures, fewer sternal wound infections and hypoglycemic episodes were reported, indicating that the pharmacy protocol may have a positive impact on patient outcomes.

Entities:  

Keywords:  hyperglycemia; hypoglycemia; postoperative complications; surgical wound infection

Year:  2014        PMID: 24623869      PMCID: PMC3940681          DOI: 10.1310/hpj4902-164

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  9 in total

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Review 2.  The Society of Thoracic Surgeons practice guideline series: Blood glucose management during adult cardiac surgery.

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Journal:  Ann Thorac Surg       Date:  1997-02       Impact factor: 4.330

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Journal:  Diabetes Care       Date:  2013-01       Impact factor: 19.112

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Journal:  J Clin Endocrinol Metab       Date:  2006-08-08       Impact factor: 5.958

7.  Cleveland Clinic cardiovascular intensive care unit insulin conversion protocol.

Authors:  Leann Olansky; Sharon Sam; Cheryl Lober; Jean-Pierre Yared; Byron Hoogwerf
Journal:  J Diabetes Sci Technol       Date:  2009-05-01

8.  Implementation of a pharmacist-led, multidisciplinary diabetes management team.

Authors:  Laurie Warrington; Phil Ayers; Anna Marie Baldwin; Virginia Wallace; Krista D Riche; Robert Saulters; Oliver Grey Waldrop; Teri Dyess; Gordon Bart Delashmet; Samuel Peeples; W Stewart Horsley; William J Harris; Kenneth Butler
Journal:  Am J Health Syst Pharm       Date:  2012-07-15       Impact factor: 2.637

Review 9.  Intravenous insulin infusion therapy: indications, methods, and transition to subcutaneous insulin therapy.

Authors:  Bruce W Bode; Susan S Braithwaite; R Dennis Steed; Paul C Davidson
Journal:  Endocr Pract       Date:  2004 Mar-Apr       Impact factor: 3.443

  9 in total
  1 in total

Review 1.  Transitioning safely from intravenous to subcutaneous insulin.

Authors:  Kathryn Evans Kreider; Lillian F Lien
Journal:  Curr Diab Rep       Date:  2015-05       Impact factor: 4.810

  1 in total

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