Literature DB >> 24621037

Spinal cord astrocytoma mimicking multifocal myelitis.

Dulce Neutel, Tiago Teodoro, Miguel Coelho, José Pimentel, Luísa Albuquerque.   

Abstract

INTRODUCTION: Differential diagnosis of acute/subacute intrinsic spinal cord lesions can be challenging. In addition, intramedullary neoplasms typically show gadolinium enhancement, mass effect, and cord expansion. CASE REPORT: We report a patient with spinal cord and brain stem lesions resembling multifocal myelitis. Magnetic resonance imaging showed no spinal cord enlargement or gadolinium enhancing. Treatment of myelitis was undertaken without stopping the progression of the disease. Biopsy was made and led to a histological diagnosis of astrocytoma. DISCUSSION: Astrocytoma must remain as a possible diagnosis of spinal cord lesions, even without typical characteristics of neoplasms. Furthermore, biopsy should always be considered when diagnosis is uncertain.

Entities:  

Keywords:  Demyelinating diseases; Non-enhancing spinal astrocytoma

Mesh:

Substances:

Year:  2014        PMID: 24621037      PMCID: PMC4116728          DOI: 10.1179/2045772313Y.0000000187

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


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3.  Magnetic resonance imaging findings in 22 cases of myelitis: comparison between patients with and without multiple sclerosis.

Authors: 
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Journal:  AJNR Am J Neuroradiol       Date:  2009-10-29       Impact factor: 3.825

5.  Nonenhancing tumors of the spinal cord.

Authors:  J Bradley White; Gary M Miller; Kennith F Layton; William E Krauss
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Review 1.  Acquired pathology of the pediatric spine and spinal cord.

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Journal:  Pediatr Radiol       Date:  2015-09-07

2.  Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours.

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Journal:  Acta Neuropathol       Date:  2022-10-20       Impact factor: 15.887

  2 in total

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