Literature DB >> 2461980

Tartrate-resistant acid ATPase as a cytochemical marker for osteoclasts.

G N Andersson1, S C Marks.   

Abstract

We present a modified histochemical method for staining osteoclasts and adjacent mononuclear cells which takes advantage of the recently described substrate specificity for ATP of osteoclastic acid phosphatase. Staining of osteoclasts using ATP as substrate exhibits by light microscopy the same tartrate resistance as conventional acidic phosphatases, without the bone surface staining seen with other substrates. This feature, coupled with specific staining of fewer vicinal mononuclear cells, makes this method potentially useful for studying osteoclast ontogeny and function.

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Year:  1989        PMID： 2461980     DOI： 10.1177/37.1.2461980

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN： 0022-1554            Impact factor:   2.479


  11 in total

1.  Tartrate-resistant purple acid phosphatase is synthesized as a latent proenzyme and activated by cysteine proteinases.

Authors:  J Ljusberg; B Ek-Rylander; G Andersson
Journal:  Biochem J       Date:  1999-10-01       Impact factor: 3.857

2.  Paramyxovirus-like nuclear inclusions identical to those of Paget's disease of bone detected in giant cells of primary oxalosis.

Authors:  P Bianco; G Silvestrini; P Ballanti; E Bonucci
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

3.  Local bone turnover in the metaphysis of the proximal tibia and the lumbar vertebra during the early periods after ovariectomy in rats.

Authors:  M Yamaura; T Nakamura; H Tsurukami; A Hijioka; K Narusawa; H Ohnishi; T Ohta; K Hosoda
Journal:  Calcif Tissue Int       Date:  1996-01       Impact factor: 4.333

4.  The Effects of Storage Conditions on the Preservation of Enzymatic Activity in Bone.

Authors:  Christi N Cosby; Nancy W Troiano; Melissa A Kacena
Journal:  J Histotechnol       Date:  2008-12       Impact factor: 0.714

5.  Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice.

Authors:  Qinggang Dai; Furong Xie; Yujiao Han; Xuhui Ma; Siru Zhou; Lingyong Jiang; Weiguo Zou; Jun Wang
Journal:  J Biol Chem       Date:  2016-11-22       Impact factor: 5.157

6.  T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts.

Authors:  Tiffany Zee; Carmine Settembre; Robert L Levine; Gerard Karsenty
Journal:  Mol Cell Biol       Date:  2012-01-17       Impact factor: 4.272

7.  Osteoclastic resorption of Ca-P biomaterials implanted in rabbit bone.

Authors:  M F Baslé; D Chappard; F Grizon; R Filmon; J Delecrin; G Daculsi; A Rebel
Journal:  Calcif Tissue Int       Date:  1993-11       Impact factor: 4.333

8.  Mild osteopetrosis in the microphthalmia-oak ridge mouse. A model for intermediate autosomal recessive osteopetrosis in humans.

Authors:  A Nii; E Steingrímsson; N G Copeland; N A Jenkins; J M Ward
Journal:  Am J Pathol       Date:  1995-12       Impact factor: 4.307

9.  mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.

Authors:  Qinggang Dai; Zhan Xu; Xuhui Ma; Ningning Niu; Siru Zhou; Furong Xie; Lingyong Jiang; Jun Wang; Weiguo Zou
Journal:  Cell Death Differ       Date:  2017-07-07       Impact factor: 15.828

10.  In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts.

Authors:  Takahiro Deguchi; Maria H Alanne; Elnaz Fazeli; Katja M Fagerlund; Paula Pennanen; Petri Lehenkari; Pekka E Hänninen; Juha Peltonen; Tuomas Näreoja
Journal:  Sci Rep       Date:  2016-03-03       Impact factor: 4.379
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