INTRODUCTION: Acute respiratory infections (ARI) are the leading cause of pediatric morbidity and mortality worldwide. Information about etiological agents of ARI in developing countries is still limited. METHODOLOGY: Throat swabs collected from children hospitalized with ARI between December 2009 and May 2010 were investigated for Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza viruses by molecular analyses. RESULTS: This study conducted in Alexandria, Egypt, was designed to determine the prevalence of several microorganisms in 156 children hospitalized with ARI. Overall, samples from 76 individuals (49%) were found to be positive for at least one pathogen, and 10 of them were positive for two agents. C. pneumoniae was the most commonly detected agent, followed by M. pneumonia and H1N1 pandemic influenza virus. Positivity for C. pneumoniae was associated with colder months and mild disease of the upper respiratory tract such as laryngitis. CONCLUSIONS: Further studies are needed to identify other possible agents of ARI (e.g., RSV, adenoviruses, other bacterial infections) in this population and to better understand the causal role of atypical bacteria detected in respiratory samples.
INTRODUCTION: Acute respiratory infections (ARI) are the leading cause of pediatric morbidity and mortality worldwide. Information about etiological agents of ARI in developing countries is still limited. METHODOLOGY: Throat swabs collected from children hospitalized with ARI between December 2009 and May 2010 were investigated for Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza viruses by molecular analyses. RESULTS: This study conducted in Alexandria, Egypt, was designed to determine the prevalence of several microorganisms in 156 children hospitalized with ARI. Overall, samples from 76 individuals (49%) were found to be positive for at least one pathogen, and 10 of them were positive for two agents. C. pneumoniae was the most commonly detected agent, followed by M. pneumonia and H1N1 pandemic influenza virus. Positivity for C. pneumoniae was associated with colder months and mild disease of the upper respiratory tract such as laryngitis. CONCLUSIONS: Further studies are needed to identify other possible agents of ARI (e.g., RSV, adenoviruses, other bacterial infections) in this population and to better understand the causal role of atypical bacteria detected in respiratory samples.
Authors: Juana Del Valle-Mendoza; Fiorella Orellana-Peralta; Alvaro Marcelo-Rodríguez; Eduardo Verne; Mónica Esquivel-Vizcarra; Wilmer Silva-Caso; Miguel Angel Aguilar-Luis; Pablo Weilg; Verónica Casabona-Oré; Claudia Ugarte; Luis J Del Valle Journal: PLoS One Date: 2017-01-27 Impact factor: 3.240
Authors: H Bühl; D Eibach; M Nagel; G Greub; N Borel; N Sarpong; T Rettig; T Pesch; S Aeby; A Klöckner; M Brunke; S Krannich; B Kreuels; E Owusu-Dabo; B Hogan; J May; B Henrichfreise Journal: New Microbes New Infect Date: 2018-01-13
Authors: Juana del Valle Mendoza; Angela Cornejo-Tapia; Pablo Weilg; Eduardo Verne; Ronald Nazario-Fuertes; Claudia Ugarte; Luis J del Valle; Tomás Pumarola Journal: J Med Virol Date: 2015-03-17 Impact factor: 2.327