Literature DB >> 24618869

Librium for bed 1, a bottle of scotch for bed 2.

Ted Welman1, Jan Man Wong, Rebecca Le Vay, Pairaw Kader.   

Abstract

A 47-year-old ex-nurse presented to the emergency department having consumed an unknown quantity of antifreeze. She was found to have a high level of ethylene glycol (the toxic component of antifreeze) in her bloodstream. Treatment is with either fomepizole or ethanol. She was treated with a loading dose of 2.5 mL/kg followed by 0.58 mL/kg/h of oral ethanol, equating to a maintenance dose of 35 mL of whisky every hour. She was placed on the gastroenterology ward next to two alcoholics recovering from acute withdrawal. It is important to appreciate the potential difficulties posed by scenarios of this type in order to provide optimum care both for the patient and those situated on the ward in the immediate vicinity. There is a requirement to compare the efficacies of fomepizole and ethanol therapy in the UK in order for a decision to be made on the most cost-effective first-line treatment.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 24618869      PMCID: PMC3962897          DOI: 10.1136/bcr-2013-202809

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  16 in total

1.  Consequences of ethylene glycol poisoning. Report of four cases and review of the literature.

Authors:  E A FRIEDMAN; J B GREENBERG; J P MERRILL; G J DAMMIN
Journal:  Am J Med       Date:  1962-06       Impact factor: 4.965

Review 2.  Ethylene glycol poisoning: case report of a record-high level and a review.

Authors:  D P Davis; K J Bramwell; R S Hamilton; S R Williams
Journal:  J Emerg Med       Date:  1997 Sep-Oct       Impact factor: 1.484

Review 3.  Fomepizole for ethylene glycol and methanol poisoning.

Authors:  Jeffrey Brent
Journal:  N Engl J Med       Date:  2009-05-21       Impact factor: 91.245

4.  National audit of antidote stocking in acute hospitals in the UK.

Authors:  Ruben H K Thanacoody; Gloria Aldridge; Willie Laing; Paul I Dargan; Stephen Nash; John P Thompson; Allister Vale; Nick Bateman; Simon Thomas
Journal:  Emerg Med J       Date:  2012-08-08       Impact factor: 2.740

5.  Ethylene glycol poisoning.

Authors:  M F Parry; R Wallach
Journal:  Am J Med       Date:  1974-07       Impact factor: 4.965

6.  Antidotes for alcohol and glycol toxicity: translating mechanisms into treatments.

Authors:  K E McMartin
Journal:  Clin Pharmacol Ther       Date:  2010-08-04       Impact factor: 6.875

7.  Acute ethylene glycol intoxication.

Authors:  J P Frommer; J C Ayus
Journal:  Am J Nephrol       Date:  1982       Impact factor: 3.754

Review 8.  Ethylene glycol poisoning.

Authors:  Peter Mygind Leth; Markil Gregersen
Journal:  Forensic Sci Int       Date:  2005-01-21       Impact factor: 2.395

Review 9.  Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

Authors:  Kenneth McMartin
Journal:  Clin Toxicol (Phila)       Date:  2009-11       Impact factor: 4.467

10.  Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole.

Authors:  Katherine J Lepik; Adrian R Levy; Boris G Sobolev; Roy A Purssell; Christopher R DeWitt; Gunnar D Erhardt; James R Kennedy; Derek E Daws; Jane L Brignall
Journal:  Ann Emerg Med       Date:  2008-07-18       Impact factor: 5.721

View more
  1 in total

1.  Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol.

Authors:  B Achappa; D Madi; T Kanchan; N K Kishanlal
Journal:  Case Rep Med       Date:  2019-01-30
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.