Literature DB >> 2461869

Restriction fragment length polymorphisms in the ETS-1 proto-oncogene. Comparison of Saudi and Western populations.

M H Parkar1, J M Seid, J M Rowson, B M Stringer, L J Vencer, R J Aur, M H Goyns.   

Abstract

We have cloned part of the ETS 1 proto-oncogene and demonstrated the presence of two polymorphic Sst I restriction sites. A probe derived from one of our clones revealed the presence of 8.3 kb, 9.5 kb and/or 11.5 kb fragments on Southern blots of human DNA samples. The relative frequencies of these alleles appear to be significantly different between Saudi and Western populations, but there are no apparent differences in these frequencies between Saudi non-leukemic and leukemic individuals.

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Year:  1988        PMID： 2461869     DOI： 10.1007/bf01939909

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  The proto-oncogene c-ets is preferentially expressed in lymphoid cells.

Authors:  J H Chen
Journal:  Mol Cell Biol       Date:  1985-11       Impact factor: 4.272

2.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

3.  Isolation of high-molecular-weight DNA from mammalian cells.

Authors:  M Gross-Bellard; P Oudet; P Chambon
Journal:  Eur J Biochem       Date:  1973-07-02

4.  Ha-ras hypervariable alleles in myelodysplasia.

Authors:  S L Thein; D G Oscier; J Flint; J S Wainscoat
Journal:  Nature       Date:  1986 May 1-7       Impact factor: 49.962

5.  Chromosomal localization of the human proto-oncogene c-ets.

Authors:  C de Taisne; A Gegonne; D Stehelin; A Bernheim; R Berger
Journal:  Nature       Date:  1984 Aug 16-22       Impact factor: 49.962

6.  Prediction of the risk of hereditary retinoblastoma, using DNA polymorphisms within the retinoblastoma gene.

Authors:  J Wiggs; M Nordenskjöld; D Yandell; J Rapaport; V Grondin; M Janson; B Werelius; R Petersen; A Craft; K Riedel
Journal:  N Engl J Med       Date:  1988-01-21       Impact factor: 91.245

7.  Translocation 4; 11 in acute lymphoblastic leukemia: clinical characteristics and prognostic significance.

Authors:  D C Arthur; C D Bloomfield; L L Lindquist; M E Nesbit
Journal:  Blood       Date:  1982-01       Impact factor: 22.113

8.  The c-ets-1 proto-oncogene is rearranged in some cases of acute lymphoblastic leukaemia.

Authors:  M H Goyns; I M Hann; J Stewart; A Gegonne; G D Birnie
Journal:  Br J Cancer       Date:  1987-11       Impact factor: 7.640
  8 in total

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