Literature DB >> 24618532

Future breakthroughs in the genetics of pulmonary arterial hypertension.

Nicholas W Morrell1.   

Abstract

Entities:  

Year:  2013        PMID： 24618532      PMCID： PMC4070807          DOI： 10.1086/674305

Source DB:  PubMed          Journal:  Pulm Circ        ISSN： 2045-8932            Impact factor:   3.017


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  11 in total

1.  Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene.

Authors:  Z Deng; J H Morse; S L Slager; N Cuervo; K J Moore; G Venetos; S Kalachikov; E Cayanis; S G Fischer; R J Barst; S E Hodge; J A Knowles
Journal:  Am J Hum Genet       Date:  2000-07-20       Impact factor: 11.025

2.  A novel channelopathy in pulmonary arterial hypertension.

Authors:  Lijiang Ma; Danilo Roman-Campos; Eric D Austin; Mélanie Eyries; Kevin S Sampson; Florent Soubrier; Marine Germain; David-Alexandre Trégouët; Alain Borczuk; Erika Berman Rosenzweig; Barbara Girerd; David Montani; Marc Humbert; James E Loyd; Robert S Kass; Wendy K Chung
Journal:  N Engl J Med       Date:  2013-07-25       Impact factor: 91.245

3.  Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension.

Authors:  K B Lane; R D Machado; M W Pauciulo; J R Thomson; J A Phillips; J E Loyd; W C Nichols; R C Trembath
Journal:  Nat Genet       Date:  2000-09       Impact factor: 38.330

4.  Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.

Authors:  R C Trembath; J R Thomson; R D Machado; N V Morgan; C Atkinson; I Winship; G Simonneau; N Galie; J E Loyd; M Humbert; W C Nichols; N W Morrell; J Berg; A Manes; J McGaughran; M Pauciulo; L Wheeler
Journal:  N Engl J Med       Date:  2001-08-02       Impact factor: 91.245

5.  Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

Authors:  Rajiv D Machado; Micheala A Aldred; Victoria James; Rachel E Harrison; Bhakti Patel; Edward C Schwalbe; Ekkehard Gruenig; Bart Janssen; Rolf Koehler; Werner Seeger; Oliver Eickelberg; Horst Olschewski; C Gregory Elliott; Eric Glissmeyer; John Carlquist; Miryoung Kim; Adam Torbicki; Anna Fijalkowska; Grzegorz Szewczyk; Jasmine Parma; Marc J Abramowicz; Nazzareno Galie; Hiroko Morisaki; Shingo Kyotani; Norifumi Nakanishi; Takayuki Morisaki; Marc Humbert; Gerald Simonneau; Olivier Sitbon; Florent Soubrier; Florence Coulet; Nicholas W Morrell; Richard C Trembath
Journal:  Hum Mutat       Date:  2006-02       Impact factor: 4.878

6.  Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension.

Authors:  A Chaouat; F Coulet; C Favre; G Simonneau; E Weitzenblum; F Soubrier; M Humbert
Journal:  Thorax       Date:  2004-05       Impact factor: 9.139

7.  FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.

Authors:  Edda Spiekerkoetter; Xuefei Tian; Jie Cai; Rachel K Hopper; Deepti Sudheendra; Caiyun G Li; Nesrine El-Bizri; Hirofumi Sawada; Roxanna Haghighat; Roshelle Chan; Leila Haghighat; Vinicio de Jesus Perez; Lingli Wang; Sushma Reddy; Mingming Zhao; Daniel Bernstein; David E Solow-Cordero; Philip A Beachy; Thomas J Wandless; Peter Ten Dijke; Marlene Rabinovitch
Journal:  J Clin Invest       Date:  2013-07-15       Impact factor: 14.808

8.  Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.

Authors:  Marine Germain; Mélanie Eyries; David Montani; Odette Poirier; Barbara Girerd; Peter Dorfmüller; Florence Coulet; Sophie Nadaud; Svetlana Maugenre; Christophe Guignabert; Wassila Carpentier; Anton Vonk-Noordegraaf; Marilyne Lévy; Ari Chaouat; Jean-Charles Lambert; Marion Bertrand; Anne-Marie Dupuy; Luc Letenneur; Mark Lathrop; Philippe Amouyel; Thomy J L de Ravel; Marion Delcroix; Eric D Austin; Ivan M Robbins; Anna R Hemnes; James E Loyd; Erika Berman-Rosenzweig; Robyn J Barst; Wendy K Chung; Gerald Simonneau; David A Trégouët; Marc Humbert; Florent Soubrier
Journal:  Nat Genet       Date:  2013-03-17       Impact factor: 38.330

9.  Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation.

Authors:  Lu Long; Xudong Yang; Mark Southwood; Junyu Lu; Stefan J Marciniak; Benjamin J Dunmore; Nicholas W Morrell
Journal:  Circ Res       Date:  2013-02-27       Impact factor: 17.367

10.  The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations.

Authors:  Benjamin J Dunmore; Kylie M Drake; Paul D Upton; Mark R Toshner; Micheala A Aldred; Nicholas W Morrell
Journal:  Hum Mol Genet       Date:  2013-05-12       Impact factor: 6.150
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  2 in total

1.  Pregnancy as a possible trigger for heritable pulmonary arterial hypertension.

Authors:  Maude Limoges; David Langleben; Benjamin D Fox; Roberta Shear; Paul Wieczorek; Lawrence G Rudski; Andrew M Hirsch; Robert D Schlesinger; Lyda Lesenko
Journal:  Pulm Circ       Date:  2016-09       Impact factor: 3.017

2.  Vasodilator responsiveness in idiopathic pulmonary arterial hypertension: identifying a distinct phenotype with distinct physiology and distinct prognosis.

Authors:  David Langleben; Stylianos Orfanos
Journal:  Pulm Circ       Date:  2017-06-20       Impact factor: 3.017
  2 in total

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