Literature DB >> 24614777

Hypoglycaemia in a patient who is non-diabetic.

Thomas Wolfenden1, Umesh Dashora, Paul Carroll.   

Abstract

A 59-year-old Caucasian man was seen in clinic following general practitioner's referral presenting with a 1-year history of hypoglycaemia. It was deemed important given his history that an insulinoma should be ruled out. The patient had an induced episode of hypoglycaemia while under medical supervision; C-peptide, insulin and insulin-like growth factor levels were measured. These results strongly suggested an insulinoma. He was subsequently referred to our local tertiary centre for surgical workup and excision of the insulinoma. This case reminds us that insulinoma, although rare, is an important differential to rule out in non-diabetic hypoglycaemia. Often the diagnosis is overlooked as their symptoms mimic many other conditions. Although there is no specific Driver and Vehicle Licensing Agency advice, we, as the healthcare provider, should be ensuring the patients inform them.

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Year:  2014        PMID: 24614777      PMCID: PMC3962922          DOI: 10.1136/bcr-2013-203260

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) positron emission tomography as a tool to localize an insulinoma or beta-cell hyperplasia in adult patients.

Authors:  Saila Kauhanen; Marko Seppänen; Heikki Minn; Risto Gullichsen; Anna Salonen; Kalle Alanen; Riitta Parkkola; Olof Solin; Jörgen Bergman; Timo Sane; Jorma Salmi; Matti Välimäki; Pirjo Nuutila
Journal:  J Clin Endocrinol Metab       Date:  2007-01-16       Impact factor: 5.958

2.  A prospective survey for insulinomas in a neurology department.

Authors:  M G Harrington; A P McGeorge; J P Ballantyne; G Beastall
Journal:  Lancet       Date:  1983-05-14       Impact factor: 79.321

3.  Insulinoma and islet cell hyperplasia: value of the calcium intraarterial stimulation test when findings of other preoperative studies are negative.

Authors:  P L Pereira; A J Roche; G W Maier; P E Huppert; F Dammann; C T Farnsworth; S H Duda; C D Claussen
Journal:  Radiology       Date:  1998-03       Impact factor: 11.105

4.  Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study.

Authors:  F J Service; M M McMahon; P C O'Brien; D J Ballard
Journal:  Mayo Clin Proc       Date:  1991-07       Impact factor: 7.616

5.  Secular trends in the presentation and management of functioning insulinoma at the Mayo Clinic, 1987-2007.

Authors:  Kimberly A Placzkowski; Adrian Vella; Geoffrey B Thompson; Clive S Grant; Carl C Reading; J William Charboneau; James C Andrews; Ricardo V Lloyd; F John Service
Journal:  J Clin Endocrinol Metab       Date:  2009-01-13       Impact factor: 5.958

Review 6.  Localization of islet cell tumors of the pancreas: a review of current techniques.

Authors:  I J Fedorak; T C Ko; D Gordon; M Flisak; R A Prinz
Journal:  Surgery       Date:  1993-03       Impact factor: 3.982

7.  Insulinoma: clinical and diagnostic features of 60 consecutive cases.

Authors:  F J Service; A J Dale; L R Elveback; N S Jiang
Journal:  Mayo Clin Proc       Date:  1976-07       Impact factor: 7.616

  7 in total

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