Literature DB >> 24614771

Shared decision-making in treatment of Merkel cell carcinoma.

Signe Muus Steffensen1, Niels Korsgaard.   

Abstract

An 82-year-old woman presented with an asymptomatic mass, rapidly growing on her left cheek for the previous 3 months. Punch biopsy of the tumour was performed, and the pathology was compatible with Merkel cell carcinoma. A resection margin of more than 1 cm would involve left oral commissura, potentially damaging speech, eating and drinking ability. The patient had a strong wish of keeping surgery simple in order to maintain quality of life. Tumour excision was performed with 1 cm resection margin, and postoperatively the patient was referred to adjuvant radiation therapy. Sensibility of upper and lower lip remained unaffected, while motor innervation of left upper lip was impaired. Despite this, the patient's ability to talk and eat was unaffected. Surgery, with adjunctive radiation therapy, is the first-line of treatment for the primary tumour. The option for a more conservative treatment is not first choice, but can be considered upon individual assessment.

Entities:  

Mesh:

Year:  2014        PMID: 24614771      PMCID: PMC3962893          DOI: 10.1136/bcr-2013-201675

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

Review 1.  Merkel cell carcinoma: a virus-induced human cancer.

Authors:  Yuan Chang; Patrick S Moore
Journal:  Annu Rev Pathol       Date:  2011-09-13       Impact factor: 23.472

2.  Sentinel lymph node biopsy in patients with Merkel cell carcinoma: an emerging role and the Westmead hospital experience.

Authors:  Julie Howle; Michael Veness
Journal:  Australas J Dermatol       Date:  2012-02       Impact factor: 2.875

3.  Brief S2k guidelines--Merkel cell carcinoma.

Authors:  Jürgen C Becker; Chalid Assaf; Dirk Vordermark; Sven N Reske; Jörg Hense; Therese Dettenborn; Oliver Seitz; Stephan Grabbe
Journal:  J Dtsch Dermatol Ges       Date:  2013-06       Impact factor: 5.584

Review 4.  Merkel cell carcinoma.

Authors:  Michael Howard Swann; Jaeyoung Yoon
Journal:  Semin Oncol       Date:  2007-02       Impact factor: 4.929

Review 5.  The role of radiation therapy in the management of skin cancers.

Authors:  Rohun Hulyalkar; Tina Rakkhit; Jorge Garcia-Zuazaga
Journal:  Dermatol Clin       Date:  2011-04       Impact factor: 3.478

6.  Predictors of survival and recurrence in the surgical treatment of merkel cell carcinoma of the extremities.

Authors:  Alex Senchenkov; Sunni A Barnes; Steven L Moran
Journal:  J Surg Oncol       Date:  2007-03-01       Impact factor: 3.454

7.  Recurrence and survival in patients undergoing sentinel lymph node biopsy for merkel cell carcinoma: analysis of 153 patients from a single institution.

Authors:  Ryan C Fields; Klaus J Busam; Joanne F Chou; Katherine S Panageas; Melissa P Pulitzer; Dennis H Kraus; Mary S Brady; Daniel G Coit
Journal:  Ann Surg Oncol       Date:  2011-03-24       Impact factor: 5.344

8.  Guidelines for the diagnosis and treatment of Merkel cell carcinoma - Cutaneous Oncology Group of the French Society of Dermatology.

Authors:  Olivia Boccara; Celine Girard; Laurent Mortier; Guido Bens; Philippe Saiag; Bernard Guillot
Journal:  Eur J Dermatol       Date:  2012 May-Jun       Impact factor: 3.328

Review 9.  [The interdisciplinary treatment of Merkel cell carcinoma: a retrospective case analysis and review of the current literature].

Authors:  B Strub; S Weindel; P Witt; J Grünert
Journal:  Zentralbl Chir       Date:  2009-09-15       Impact factor: 0.942

10.  A practical update of surgical management of merkel cell carcinoma of the skin.

Authors:  Patricia Tai
Journal:  ISRN Surg       Date:  2013-01-30
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  1 in total

1.  Unknown primary Merkel cell carcinoma with cutaneous spread.

Authors:  João Vasco Barreira; Margarida Moura Valejo Coelho; Catarina Ribeiro; Mónica Semedo
Journal:  BMJ Case Rep       Date:  2019-02-21
  1 in total

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