F Binder-Foucard1, N Bossard2, P Delafosse3, A Belot4, A-S Woronoff5, L Remontet2. 1. Réseau français des registres des cancers, Francim, 31073 Toulouse, France; Registre des cancers du Bas-Rhin, laboratoire d'épidémiologie et de santé publique, EA 3430, faculté de médecine, université de Strasbourg, 4, rue Kirschleger, 67085 Strasbourg cedex, France; Service de santé publique, hôpitaux universitaires de Strasbourg, 67000 Strasbourg, France. Electronic address: florence.binder@unistra.fr. 2. Service de biostatistique, hospices civils de Lyon, centre hospitalier Lyon-Sud, 69424 Lyon, France; Université Lyon-I, 69622 Villeurbanne, France; UMR 5558, laboratoire biostatistique santé, CNRS, 69495 Pierre-Bénite cedex, France. 3. Réseau français des registres des cancers, Francim, 31073 Toulouse, France; Registre du cancer du département de l'Isère, CHU de Grenoble, 38000 Grenoble, France. 4. Service de biostatistique, hospices civils de Lyon, centre hospitalier Lyon-Sud, 69424 Lyon, France; Université Lyon-I, 69622 Villeurbanne, France; UMR 5558, laboratoire biostatistique santé, CNRS, 69495 Pierre-Bénite cedex, France; Département des maladies chroniques et traumatismes, Institut de veille sanitaire, 94410 Saint-Maurice, France. 5. Réseau français des registres des cancers, Francim, 31073 Toulouse, France; Registre des tumeurs du Doubs et du Territoire de Belfort, EA 3181, CHRU de Besançon, 25030 Besançon cedex, France.
Abstract
BACKGROUND: Cancer incidence and mortality estimates for 19 cancers (among solid tumors) are presented for France between 1980 and 2012. METHODS: Incidence data were collected from 21 local registries and correspond to invasive cancers diagnosed between 1975 and 2009. Mortality data for the same period were provided by the Institut national de la santé et de la recherche médicale. The national incidence estimates were based on the use of mortality as a correlate of incidence. The observed incidence and mortality data were modeled using an age-period-cohort model. The numbers of incident cases and deaths for 2010-2012 are the result of short-term projections. RESULTS: In 2012, the study estimated that 355,000 new cases of cancer (excluding non-melanoma skin cancer) and 148,000 deaths from cancer occurred in France. The incidence trend was not linear over the study period. After a constant increase from 1980 onwards, the incidence of cancer in men declined between 2005 and 2012. This recent decrease is largely related to the reduction in the incidence of prostate cancer. In women, the rates stabilized, mainly due to a change in breast cancer incidence. Mortality from most cancer types declined over the study period. A combined analysis of incidence and mortality by cancer site distinguished cancers with declining incidence and mortality (e.g., stomach) and cancers with increasing incidence and mortality (e.g., lung cancer in women). Some other cancers had rising incidence but declining mortality (e.g., thyroid). CONCLUSION: This study reveals recent changes in cancer incidence trends, particularly regarding breast and prostate cancers.
BACKGROUND:Cancer incidence and mortality estimates for 19 cancers (among solid tumors) are presented for France between 1980 and 2012. METHODS: Incidence data were collected from 21 local registries and correspond to invasive cancers diagnosed between 1975 and 2009. Mortality data for the same period were provided by the Institut national de la santé et de la recherche médicale. The national incidence estimates were based on the use of mortality as a correlate of incidence. The observed incidence and mortality data were modeled using an age-period-cohort model. The numbers of incident cases and deaths for 2010-2012 are the result of short-term projections. RESULTS: In 2012, the study estimated that 355,000 new cases of cancer (excluding non-melanoma skin cancer) and 148,000 deaths from cancer occurred in France. The incidence trend was not linear over the study period. After a constant increase from 1980 onwards, the incidence of cancer in men declined between 2005 and 2012. This recent decrease is largely related to the reduction in the incidence of prostate cancer. In women, the rates stabilized, mainly due to a change in breast cancer incidence. Mortality from most cancer types declined over the study period. A combined analysis of incidence and mortality by cancer site distinguished cancers with declining incidence and mortality (e.g., stomach) and cancers with increasing incidence and mortality (e.g., lung cancer in women). Some other cancers had rising incidence but declining mortality (e.g., thyroid). CONCLUSION: This study reveals recent changes in cancer incidence trends, particularly regarding breast and prostate cancers.
Authors: G Defossez; Z Uhry; P Delafosse; E Dantony; T d'Almeida; S Plouvier; N Bossard; A M Bouvier; F Molinié; A S Woronoff; M Colonna; P Grosclaude; L Remontet; A Monnereau Journal: BMC Cancer Date: 2021-06-24 Impact factor: 4.430