Literature DB >> 24611212

Schedules of controlled substances: temporary placement of 10 synthetic cathinones into Schedule I. Final order.

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Abstract

The Deputy Administrator of the Drug Enforcement Administration (DEA) is issuing this final order to temporarily schedule 10 synthetic cathinones into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act (CSA). The 10 substances are: 4-methyl-N-ethylcathinone (``4-MEC''); 4-methyl-alpha-pyrrolidinopropiophenone (``4-MePPP''); alpha-pyrrolidinopentiophenone (``[alpha]-PVP''); 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one (``butylone''); 2-(methylamino)-1-phenylpentan-1-one (``pentedrone''); 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one (``pentylone''); 4-fluoro-N-methylcathinone (``4-FMC''); 3-fluoro-N-methylcathinone (``3-FMC''); 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (``naphyrone''); and alpha-pyrrolidinobutiophenone (``[alpha]-PBP''). This action is based on a finding by the Deputy Administrator that the placement of these synthetic cathinones and their optical, positional, and geometric isomers, salts and salts of isomers into schedule I of the CSA is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, import, export, engage in research, conduct instructional activities, and possess), or propose to handle these synthetic cathinones.

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Year:  2014        PMID: 24611212

Source DB:  PubMed          Journal:  Fed Regist        ISSN: 0097-6326


  21 in total

1.  Comparative Behavioral Pharmacology of Three Pyrrolidine-Containing Synthetic Cathinone Derivatives.

Authors:  Michael B Gatch; Sean B Dolan; Michael J Forster
Journal:  J Pharmacol Exp Ther       Date:  2015-05-21       Impact factor: 4.030

2.  Synthetic cathinones and their rewarding and reinforcing effects in rodents.

Authors:  Lucas R Watterson; M Foster Olive
Journal:  Adv Neurosci (Hindawi)       Date:  2014-06-04

3.  Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats.

Authors:  Jennifer E Naylor; Kevin B Freeman; Bruce E Blough; William L Woolverton; Sally L Huskinson
Journal:  Drug Alcohol Depend       Date:  2015-02-11       Impact factor: 4.492

4.  Emerging threats in addiction: will novel psychoactive substances contribute to exacerbating the ongoing drug overdose epidemic?

Authors:  F Scott Hall; Klaus A Miczek
Journal:  Psychopharmacology (Berl)       Date:  2019-03       Impact factor: 4.530

5.  Discriminative and locomotor effects of five synthetic cathinones in rats and mice.

Authors:  Michael B Gatch; Margaret A Rutledge; Michael J Forster
Journal:  Psychopharmacology (Berl)       Date:  2014-10-05       Impact factor: 4.530

6.  Self-administration and behavioral economics of second-generation synthetic cathinones in male rats.

Authors:  S L Huskinson; J E Naylor; E A Townsend; J K Rowlett; B E Blough; K B Freeman
Journal:  Psychopharmacology (Berl)       Date:  2016-11-28       Impact factor: 4.530

7.  Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats.

Authors:  Brenda M Gannon; Kayla I Galindo; Melson P Mesmin; Agnieszka Sulima; Kenner C Rice; Gregory T Collins
Journal:  Neuropharmacology       Date:  2017-08-12       Impact factor: 5.250

8.  In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats.

Authors:  Shawn M Aarde; Kevin M Creehan; Sophia A Vandewater; Tobin J Dickerson; Michael A Taffe
Journal:  Psychopharmacology (Berl)       Date:  2015-05-01       Impact factor: 4.530

9.  Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters.

Authors:  R Kolanos; F Sakloth; A D Jain; J S Partilla; M H Baumann; R A Glennon
Journal:  ACS Chem Neurosci       Date:  2015-08-11       Impact factor: 4.418

10.  In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant.

Authors:  Madeleine J Swortwood; Jeremy Carlier; Kayla N Ellefsen; Ariane Wohlfarth; Xingxing Diao; Marta Concheiro-Guisan; Robert Kronstrand; Marilyn A Huestis
Journal:  Bioanalysis       Date:  2015-12-09       Impact factor: 2.681

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