Literature DB >> 24610094

Translated chemical reaction networks.

Matthew D Johnston1.   

Abstract

Many biochemical and industrial applications involve complicated networks of simultaneously occurring chemical reactions. Under the assumption of mass action kinetics, the dynamics of these chemical reaction networks are governed by systems of polynomial ordinary differential equations. The steady states of these mass action systems have been analyzed via a variety of techniques, including stoichiometric network analysis, deficiency theory, and algebraic techniques (e.g., Gröbner bases). In this paper, we present a novel method for characterizing the steady states of mass action systems. Our method explicitly links a network's capacity to permit a particular class of steady states, called toric steady states, to topological properties of a generalized network called a translated chemical reaction network. These networks share their reaction vectors with their source network but are permitted to have different complex stoichiometries and different network topologies. We apply the results to examples drawn from the biochemical literature.

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Year:  2014        PMID: 24610094     DOI: 10.1007/s11538-014-9947-5

Source DB:  PubMed          Journal:  Bull Math Biol        ISSN: 0092-8240            Impact factor:   1.758


  4 in total

1.  A computational approach to persistence, permanence, and endotacticity of biochemical reaction systems.

Authors:  Matthew D Johnston; Casian Pantea; Pete Donnell
Journal:  J Math Biol       Date:  2015-05-19       Impact factor: 2.259

2.  Conditions for extinction events in chemical reaction networks with discrete state spaces.

Authors:  Matthew D Johnston; David F Anderson; Gheorghe Craciun; Robert Brijder
Journal:  J Math Biol       Date:  2017-09-26       Impact factor: 2.259

3.  A Deficiency-Based Approach to Parametrizing Positive Equilibria of Biochemical Reaction Systems.

Authors:  Matthew D Johnston; Stefan Müller; Casian Pantea
Journal:  Bull Math Biol       Date:  2018-12-31       Impact factor: 1.758

4.  Derivation of stationary distributions of biochemical reaction networks via structure transformation.

Authors:  Hyukpyo Hong; Jinsu Kim; M Ali Al-Radhawi; Eduardo D Sontag; Jae Kyoung Kim
Journal:  Commun Biol       Date:  2021-05-24
  4 in total

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