Literature DB >> 24609799

Mechanisms mediating renal sympathetic nerve activation in obesity-related hypertension.

W Chen1, S Leo, C Weng, X Yang, Y Wu, X Tang.   

Abstract

Excessive renal sympathetic nerve activation may be one of the mechanisms underlying obesity-related hypertension. Impaired baroreflex sensitivity, adipokine disorders-such as leptin, adiponectin, and resistin-activation of the renin-angiotensin system, hyperinsulinemia, insulin resistance, and renal sodium retention present in obesity increase renal sympathetic nerve activity, thus contributing to the development of hypertension. Renal sympathetic denervation reduces both renal sympathetic activity and blood pressure in patients with obesity-related hypertension.

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Year:  2015        PMID： 24609799     DOI： 10.1007/s00059-014-4072-7

Source DB:  PubMed          Journal:  Herz        ISSN： 0340-9937            Impact factor:   1.443


  76 in total

1.  Role of norepinephrine & angiotensin II in the neural control of renal sodium & water handling in spontaneously hypertensive rats.

Authors:  I M Salman; M A Sattar; O Z Ameer; N A Abdullah; M F Yam; H M Salman; M H A Khan; E J Johns
Journal:  Indian J Med Res       Date:  2010-06       Impact factor: 2.375

2.  AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity.

Authors:  Carine M Boustany; David R Brown; David C Randall; Lisa A Cassis
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2005-03-17       Impact factor: 3.619

3.  Central resistin enhances renal sympathetic nerve activity via phosphatidylinositol 3-kinase but reduces the activity to brown adipose tissue via extracellular signal-regulated kinase 1/2.

Authors:  S Kosari; J A Rathner; E Badoer
Journal:  J Neuroendocrinol       Date:  2012-11       Impact factor: 3.627

4.  Enhanced angiotensin II-induced activation of Na+, K+-ATPase in the proximal tubules of obese Zucker rats.

Authors:  Sonal Shah; Tahir Hussain
Journal:  Clin Exp Hypertens       Date:  2006-01       Impact factor: 1.749

5.  Mechanisms mediating renal sympathetic activation to leptin in obesity.

Authors:  Donald A Morgan; Daniel R Thedens; Robert Weiss; Kamal Rahmouni
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2008-09-24       Impact factor: 3.619

6.  Blunted natriuretic response to a high-sodium meal in obese dogs. Role of renal nerves.

Authors:  S Kassab; S Patterson; F C Wilkins; H L Mizelle; G A Reinhart; J P Granger
Journal:  Hypertension       Date:  1994-06       Impact factor: 10.190

7.  Aliskiren reduces body-weight gain, adiposity and plasma leptin during diet-induced obesity.

Authors:  Paula Stucchi; Victoria Cano; Mariano Ruiz-Gayo; María S Fernández-Alfonso
Journal:  Br J Pharmacol       Date:  2009-08-19       Impact factor: 8.739

8.  Impairment of sympathetic baroreceptor reflexes in obese Zucker rats.

Authors:  Ann M Schreihofer; Daniel A Mandel; Susan C Mobley; David W Stepp
Journal:  Am J Physiol Heart Circ Physiol       Date:  2007-08-17       Impact factor: 4.733

9.  Candesartan and insulin reduce renal sympathetic nerve activity in hypertensive type 1 diabetic rats.

Authors:  Chie Takimoto; Hiroo Kumagai; Motohisa Osaka; Katsufumi Sakata; Toshiko Onami; Tadashi Kamayachi; Kamon Iigaya; Koichi Hayashi; Takao Saruta; Hiroshi Itoh
Journal:  Hypertens Res       Date:  2008-10       Impact factor: 3.872

10.  Effects of renal denervation on sympathetic activation, blood pressure, and glucose metabolism in patients with resistant hypertension.

Authors:  Markus P Schlaich; Dagmara Hering; Paul Sobotka; Henry Krum; Gavin W Lambert; Elisabeth Lambert; Murray D Esler
Journal:  Front Physiol       Date:  2012-02-02       Impact factor: 4.566
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1.  Systemic PPARγ deletion causes severe disturbance in fluid homeostasis in mice.

Authors:  Li Zhou; Alexandra Panasiuk; Maicy Downton; Daqiang Zhao; Baoxue Yang; Zhanjun Jia; Tianxin Yang
Journal:  Physiol Genomics       Date:  2015-09-01       Impact factor: 3.107

2.  Prehypertension in adolescents with cardiovascular risk: a comparison between type 1 diabetic patients and overweight subjects.

Authors:  Valentina Giacchi; Tiziana Timpanaro; Donatella Lo Presti; Stefano Passanisi; Carmine Mattia; Pasqua Betta; Chiara Grasso; Manuela Caruso; Pietro Sciacca
Journal:  BMC Res Notes       Date:  2016-02-24

Review 3.  Interplay between baroreflex sensitivity, obesity and related cardiometabolic risk factors (Review).

Authors:  Sofia K Konstantinidou; Georgia Argyrakopoulou; Nicholas Tentolouris; Vangelis Karalis; Alexander Kokkinos
Journal:  Exp Ther Med       Date:  2021-11-23       Impact factor: 2.447

Review 4.  Autonomic Nervous System in Obesity and Insulin-Resistance-The Complex Interplay between Leptin and Central Nervous System.

Authors:  Benedetta Russo; Marika Menduni; Patrizia Borboni; Fabiana Picconi; Simona Frontoni
Journal:  Int J Mol Sci       Date:  2021-05-14       Impact factor: 5.923

5.  The QardioArm Blood Pressure App for Self-Measurement in an Obese Population: Validation Study Using the European Society of Hypertension International Protocol Revision 2010.

Authors:  Victoria Mazoteras-Pardo; Ricardo Becerro-De-Bengoa-Vallejo; Marta Elena Losa-Iglesias; Daniel López-López; Patricia Palomo-López; David Rodríguez-Sanz; César Calvo-Lobo
Journal:  JMIR Mhealth Uhealth       Date:  2018-10-25       Impact factor: 4.773
  5 in total

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