Literature DB >> 24607398

When half is better than the whole: advances in haploid embryonic stem cell technology.

Chikara Kokubu1, Junji Takeda2.   

Abstract

Recent advances in embryonic stem cell (ESC) derivation and genome editing offer efficient platforms for genetic screening. In this issue, Li et al. and Leeb et al., respectively, expand such applications by generating haploid rat ESCs for screening, mutagenesis, and CRISPR-Cas-mediated gene targeting and by developing a forward genetic screen for interrogating haploid mESCs.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24607398     DOI： 10.1016/j.stem.2014.02.001

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  6 in total

1.  Haploid embryonic stem cells can be enriched and maintained by simple filtration.

Authors:  Chao Qu; Meng Yan; Suming Yang; Lingbo Wang; Qi Yin; Yuan Liu; Yeguang Chen; Jinsong Li
Journal:  J Biol Chem       Date:  2018-02-15       Impact factor: 5.157

2.  Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.

Authors:  Masahiro Tokunaga; Chikara Kokubu; Yusuke Maeda; Jun Sese; Kyoji Horie; Nakaba Sugimoto; Taroh Kinoshita; Kosuke Yusa; Junji Takeda
Journal:  BMC Genomics       Date:  2014-11-24       Impact factor: 3.969

3.  Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development.

Authors:  Meizhu Bai; Yujiao Han; Yuxuan Wu; Jiaoyang Liao; Lin Li; Lijun Wang; Qing Li; Wenhui Xing; Luonan Chen; Weiguo Zou; Jinsong Li
Journal:  PLoS Biol       Date:  2019-07-02       Impact factor: 8.029

4.  Dysregulated Gene Expression of Imprinted and X-Linked Genes: A Link to Poor Development of Bovine Haploid Androgenetic Embryos.

Authors:  Luis Aguila; Joao Suzuki; Amanda B T Hill; Mónica García; Karine de Mattos; Jacinthe Therrien; Lawrence C Smith
Journal:  Front Cell Dev Biol       Date:  2021-03-18

5.  Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis.

Authors:  Ayako Yamanishi; Atsushi Matsuba; Ryohei Kondo; Rie Akamatsu; Sachiyo Tanaka; Masahiro Tokunaga; Kyoji Horie; Chikara Kokubu; Yasumasa Ishida; Junji Takeda
Journal:  Nucleic Acids Res       Date:  2018-06-01       Impact factor: 16.971

6.  Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency.

Authors:  Andreas Lackner; Robert Sehlke; Marius Garmhausen; Giuliano Giuseppe Stirparo; Michelle Huth; Fabian Titz-Teixeira; Petra van der Lelij; Julia Ramesmayer; Henry F Thomas; Meryem Ralser; Laura Santini; Elena Galimberti; Mihail Sarov; A Francis Stewart; Austin Smith; Andreas Beyer; Martin Leeb
Journal:  EMBO J       Date:  2021-03-09       Impact factor: 14.012
  6 in total

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