Literature DB >> 24606780

Antipsychotic prescription in children and adolescents: an analysis of data from a German statutory health insurance company from 2005 to 2012.

Christian J Bachmann1, Thomas Lempp, Gerd Glaeske, Falk Hoffmann.   

Abstract

BACKGROUND: Despite sparse documentation of their long-term therapeutic effects and side effects, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in recent years, both in the USA and in Europe. No current data are available about antipsychotic prescriptions for this age group in Germany.
METHODS: Data from the largest statutory health insurance fund in Germany (BARMER GEK) were studied to identify antipsychotic prescriptions for children and adolescents (age 0-19 years) from 2005 to 2012 and analyze them with respect to age, sex, drug prescribed, prescribing medical specialty, and any observable secular trends.
RESULTS: The percentage of children and adolescents receiving a prescription for an antipsychotic drug rose from 0.23% in 2005 to 0.32% in 2012. In particular, atypical antipsychotic drugs were prescribed more frequently over time (from 0.10% in 2005 to 0.24% in 2012). The rise in antipsychotic prescriptions was particularly marked among 10- to 14-year-olds (from 0.24% to 0.43%) and among 15- to 19-year-olds (from 0.34% to 0.54%). The prescribing physicians were mostly either child and adolescent psychiatrists or pediatricians; the most commonly prescribed drugs were risperidone and pipamperone. Risperidone was most commonly prescribed for patients with hyperkinetic disorders and conduct disorders.
CONCLUSION: In Germany as in other industrialized countries, antipsychotic drugs have come to be prescribed more frequently for children and adolescents in ecent years. The German figures, while still lower than those from North America, are in the middle range of figures from European countries. The causes of the increase should be critically examined; if appropriate, the introduction of prescribing guidelines of a more restrictive nature could be considered.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 24606780      PMCID: PMC3950759          DOI: 10.3238/arztebl.2014.0025

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  47 in total

1.  [Increase in incidence of drug treatments, ethical principles and conflict of interest in cooperation with the pharmaceutical industry].

Authors:  Johannes Hebebrand; Bernhard Blanz; Beate Herpertz-Dahlmann; Gerd Lehmkuhl
Journal:  Z Kinder Jugendpsychiatr Psychother       Date:  2012-05

2.  A European perspective on paedo-psychiatric pharmacoepidemiology.

Authors:  Hans-Christoph Steinhausen
Journal:  World Psychiatry       Date:  2013-06       Impact factor: 49.548

3.  Evidence-based recommendations for monitoring safety of second generation antipsychotics in children and youth.

Authors:  Tamara Pringsheim; Constadina Panagiotopoulos; Jana Davidson; Josephine Ho
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2011-08

4.  Time Trends in Psychopathology. A 21-year comparison from Germany.

Authors:  Sylvia Eimecke; Jan Pauschardt; Helmut Remschmidt; Reinhard Walter; Fritz Mattejat
Journal:  Z Kinder Jugendpsychiatr Psychother       Date:  2011-05

5.  Prevalence of psychiatric disorders in youths across five sectors of care.

Authors:  A F Garland; R L Hough; K M McCabe; M Yeh; P A Wood; G A Aarons
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2001-04       Impact factor: 8.829

6.  Psychopharmacological treatment in children and adolescents with autism spectrum disorders in Germany.

Authors:  Christian J Bachmann; Thomas Manthey; Inge Kamp-Becker; Gerd Glaeske; Falk Hoffmann
Journal:  Res Dev Disabil       Date:  2013-06-07

7.  Prevalence of emotional and behavioural disorders in German children and adolescents: a meta-analysis.

Authors:  Claus Barkmann; Michael Schulte-Markwort
Journal:  J Epidemiol Community Health       Date:  2010-10-01       Impact factor: 3.710

8.  Use of antipsychotic drugs among Dutch youths between 1997 and 2005.

Authors:  Luuk J Kalverdijk; Hilde Tobi; Paul B van den Berg; Janelle Buiskool; Leonie Wagenaar; Ruud B Minderaa; Lolkje T W de Jong-van den Berg
Journal:  Psychiatr Serv       Date:  2008-05       Impact factor: 3.084

Review 9.  Antipsychotics in children and adolescents: increasing use, evidence for efficacy and safety concerns.

Authors:  Benedetto Vitiello; Christoph Correll; Barbara van Zwieten-Boot; Alessandro Zuddas; Mara Parellada; Celso Arango
Journal:  Eur Neuropsychopharmacol       Date:  2009-05-24       Impact factor: 4.600

10.  Antidepressant and antipsychotic use in an Italian pediatric population.

Authors:  Antonio Clavenna; Margherita Andretta; Paola Pilati; Maurizio Dusi; Michele Gangemi; Maria Beatrice Gattoni; Giuseppe Lombardo; Leonardo Zoccante; Luigi Mezzalira; Maurizio Bonati
Journal:  BMC Pediatr       Date:  2011-05-23       Impact factor: 2.125

View more
  31 in total

1.  Combined stimulant and antipsychotic treatment in adolescents with attention-deficit/hyperactivity disorder: a cross-sectional observational structural MRI study.

Authors:  L J S Schweren; C A Hartman; M P Zwiers; D J Heslenfeld; D van der Meer; B Franke; J Oosterlaan; J K Buitelaar; P J Hoekstra
Journal:  Eur Child Adolesc Psychiatry       Date:  2014-11-14       Impact factor: 4.785

2.  Early-life risperidone enhances locomotor responses to amphetamine during adulthood.

Authors:  Bobbie Lee Stubbeman; Clifford J Brown; Justin R Yates; Mark E Bardgett
Journal:  Eur J Pharmacol       Date:  2017-07-14       Impact factor: 4.432

3.  Antipsychotic prescribing in youths: a French community-based study from 2006 to 2013.

Authors:  Hélène Verdoux; Elodie Pambrun; Sébastien Cortaredona; Marie Tournier; Pierre Verger
Journal:  Eur Child Adolesc Psychiatry       Date:  2015-01-07       Impact factor: 4.785

Review 4.  Pharmacological treatment of disruptive behavior in children with fetal alcohol spectrum disorder.

Authors:  Gideon Koren
Journal:  Paediatr Drugs       Date:  2015-06       Impact factor: 3.022

5.  Determination of psychotropic use in children and adolescents from a prescription database: methodological issues.

Authors:  Christian J Bachmann; Falk Hoffmann
Journal:  Psychopharmacology (Berl)       Date:  2014-08-15       Impact factor: 4.530

6.  Psychotropic medication in children and adolescents.

Authors:  Gerd Lehmkuhl; Ingrid Schubert
Journal:  Dtsch Arztebl Int       Date:  2014-01-17       Impact factor: 5.594

7.  More patients in less time.

Authors:  Giulio Calia
Journal:  Dtsch Arztebl Int       Date:  2014-05-16       Impact factor: 5.594

8.  In reply.

Authors:  Christian J Bachmann; Falk Hoffmann
Journal:  Dtsch Arztebl Int       Date:  2014-05-16       Impact factor: 5.594

9.  Administering shortages.

Authors:  Terje Neraal
Journal:  Dtsch Arztebl Int       Date:  2014-05-16       Impact factor: 5.594

10.  Outpatient antipsychotic drug use in children and adolescents in Germany between 2004 and 2011.

Authors:  Carsten Schröder; Michael Dörks; Bianca Kollhorst; Tilo Blenk; Ralf W Dittmann; Edeltraut Garbe; Oliver Riedel
Journal:  Eur Child Adolesc Psychiatry       Date:  2016-09-13       Impact factor: 4.785

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.