BACKGROUND: Data on the micronutrient levels in children with cystic fibrosis (CF) are not available from developing countries, wherein the nutritional profile of children is quite different from that of Western countries. METHODS: Levels of fat-soluble vitamins (A, D, and E) and trace metals (iron, copper, and zinc) were measured in 27 CF cases and 27 controls. RESULTS: CF cases had significantly low levels of all studied micronutrients compared with controls, and the levels were even lower in cases with exacerbation than in stable CF cases. Prevalence of deficiency of vitamin D, vitamin E, iron, copper, and zinc was significantly higher in cases than in controls, whereas vitamin A deficiency was almost equal in both the groups. CONCLUSION: The prevalence of deficiency of vitamins A, D, and E and iron, copper, and zinc was high in CF cases, and their levels were significantly lower in cases than controls. CF cases should be regularly monitored for these micronutrients, and appropriate supplementation should be considered.
BACKGROUND: Data on the micronutrient levels in children with cystic fibrosis (CF) are not available from developing countries, wherein the nutritional profile of children is quite different from that of Western countries. METHODS: Levels of fat-soluble vitamins (A, D, and E) and trace metals (iron, copper, and zinc) were measured in 27 CF cases and 27 controls. RESULTS: CF cases had significantly low levels of all studied micronutrients compared with controls, and the levels were even lower in cases with exacerbation than in stable CF cases. Prevalence of deficiency of vitamin D, vitamin E, iron, copper, and zinc was significantly higher in cases than in controls, whereas vitamin A deficiency was almost equal in both the groups. CONCLUSION: The prevalence of deficiency of vitamins A, D, and E and iron, copper, and zinc was high in CF cases, and their levels were significantly lower in cases than controls. CF cases should be regularly monitored for these micronutrients, and appropriate supplementation should be considered.
Authors: Dušan Garić; Juan B De Sanctis; Gabriella Wojewodka; Daniel Houle; Shanon Cupri; Asmahan Abu-Arish; John W Hanrahan; Marian Hajduch; Elias Matouk; Danuta Radzioch Journal: J Mol Med (Berl) Date: 2017-07-10 Impact factor: 4.599
Authors: Moon Jeong Lee; Jessica A Alvarez; Ellen M Smith; David W Killilea; James F Chmiel; Patricia M Joseph; Ruth E Grossmann; Amit Gaggar; Thomas R Ziegler; Vin Tangpricha Journal: Nutr Clin Pract Date: 2015-06-15 Impact factor: 3.080
Authors: Amanda Centorame; Daciana Catalina Dumut; Mina Youssef; Martin Ondra; Irenej Kianicka; Juhi Shah; Radu Alexandru Paun; Tomas Ozdian; John W Hanrahan; Ekaterina Gusev; Basil Petrof; Marian Hajduch; Radu Pislariu; Juan Bautista De Sanctis; Danuta Radzioch Journal: Front Pharmacol Date: 2022-05-20 Impact factor: 5.988
Authors: Ana Luiza Melo Dos Santos; Helen de Melo Santos; Marina Bettiol Nogueira; Hugo Tadashi Oshiro Távora; Maria de Lourdes Jaborandy Paim da Cunha; Renata Belém Pessoa de Melo Seixas; Luciana de Freitas Velloso Monte; Elisa de Carvalho Journal: Pediatr Gastroenterol Hepatol Nutr Date: 2018-10-10
Authors: Adam J Causer; Janis K Shute; Michael H Cummings; Anthony I Shepherd; Mathieu Gruet; Joseph T Costello; Stephen Bailey; Martin Lindley; Clare Pearson; Gary Connett; Mark I Allenby; Mary P Carroll; Thomas Daniels; Zoe L Saynor Journal: Redox Biol Date: 2020-01-23 Impact factor: 11.799
Authors: Marlene Fabiola Escobedo-Monge; Enrique Barrado; Carmen Alonso Vicente; María Antonieta Escobedo-Monge; María Carmen Torres-Hinojal; José Manuel Marugán-Miguelsanz; María Paz Redondo Del Río Journal: Nutrients Date: 2020-10-30 Impact factor: 5.717
Authors: Arm Luthful Kabir; Sudipta Roy; Rahat Bin Habib; Kazi Selim Anwar; Md Abid Hossain Mollah; Ruhul Amin; Al Amin Mridha; Jasim Uddin Majumder; Md Delwar Hossain; Nazmul Haque; Shakil Ahmed; Mohammod Jobayer Chisti Journal: Glob Pediatr Health Date: 2020-10-30