OBJECTIVE: To establish a statewide network to detect, control, and prevent the spread of carbapenem-resistant Enterobacteriaceae (CRE) in a region with a low incidence of CRE infection. DESIGN: Implementation of the Drug Resistant Organism Prevention and Coordinated Regional Epidemiology (DROP-CRE) Network. SETTING AND PARTICIPANTS: Oregon infection prevention and microbiology laboratory personnel, including 48 microbiology laboratories, 62 acute care facilities, and 140 long-term care facilities. METHODS: The DROP-CRE working group, comprising representatives from academic institutions and public health, convened an interdisciplinary advisory committee to assist with planning and implementation of CRE epidemiology and control efforts. The working group established a statewide CRE definition and surveillance plan; increased the state laboratory capacity to perform the modified Hodge test and polymerase chain reaction for carbapenemases in real time; and administered surveys that assessed the needs and capabilities of Oregon infection prevention and laboratory personnel. Results of these inquiries informed CRE education and the response plan. RESULTS: Of 60 CRE reported from November 2010 through April 2013, only 3 were identified as carbapenemase producers; the cases were not linked, and no secondary transmission was found. Microbiology laboratories, acute care facilities, and long-term care facilities reported lacking carbapenemase testing capability, reliable interfacility communication, and CRE awareness, respectively. Survey findings informed the creation of the Oregon CRE Toolkit, a state-specific CRE guide booklet. CONCLUSIONS: A regional epidemiology surveillance and response network has been implemented in Oregon in advance of widespread CRE transmission. Prospective surveillance will determine whether this collaborative approach will be successful at forestalling the emergence of this important healthcare-associated pathogen.
OBJECTIVE: To establish a statewide network to detect, control, and prevent the spread of carbapenem-resistant Enterobacteriaceae (CRE) in a region with a low incidence of CRE infection. DESIGN: Implementation of the Drug Resistant Organism Prevention and Coordinated Regional Epidemiology (DROP-CRE) Network. SETTING AND PARTICIPANTS: Oregon infection prevention and microbiology laboratory personnel, including 48 microbiology laboratories, 62 acute care facilities, and 140 long-term care facilities. METHODS: The DROP-CRE working group, comprising representatives from academic institutions and public health, convened an interdisciplinary advisory committee to assist with planning and implementation of CRE epidemiology and control efforts. The working group established a statewide CRE definition and surveillance plan; increased the state laboratory capacity to perform the modified Hodge test and polymerase chain reaction for carbapenemases in real time; and administered surveys that assessed the needs and capabilities of Oregon infection prevention and laboratory personnel. Results of these inquiries informed CRE education and the response plan. RESULTS: Of 60 CRE reported from November 2010 through April 2013, only 3 were identified as carbapenemase producers; the cases were not linked, and no secondary transmission was found. Microbiology laboratories, acute care facilities, and long-term care facilities reported lacking carbapenemase testing capability, reliable interfacility communication, and CRE awareness, respectively. Survey findings informed the creation of the Oregon CRE Toolkit, a state-specific CRE guide booklet. CONCLUSIONS: A regional epidemiology surveillance and response network has been implemented in Oregon in advance of widespread CRE transmission. Prospective surveillance will determine whether this collaborative approach will be successful at forestalling the emergence of this important healthcare-associated pathogen.
Authors: Karim E Morey; Robert Vega; P Maureen Cassidy; Genevieve L Buser; Jaipreet K Rayar; Jeffrey A Myers; Scott J Weissman; Zintars G Beldavs; Christopher D Pfeiffer Journal: Antimicrob Agents Chemother Date: 2016-12-27 Impact factor: 5.191
Authors: Genevieve L Buser; P Maureen Cassidy; Margaret C Cunningham; Susan Rudin; Andrea M Hujer; Robert Vega; Jon P Furuno; Steven H Marshall; Paul G Higgins; Michael R Jacobs; Meredith S Wright; Mark D Adams; Robert A Bonomo; Christopher D Pfeiffer; Zintars G Beldavs Journal: Infect Control Hosp Epidemiol Date: 2017-09-05 Impact factor: 3.254
Authors: Genevieve L Buser; P Maureen Cassidy; Christopher D Pfeiffer; John M Townes; Karim E Morey; Jaipreet Rayar; Kirthi K Kutumbaka; Sukkyun Han; Cesar Nadala; Mansour Samadpour; Scott J Weissman; Robert Vega; Zintars G Beldavs Journal: IDCases Date: 2017-06-15
Authors: Roberta Gazzarata; Maria Eugenia Monteverde; Carmelina Ruggiero; Norbert Maggi; Dalia Palmieri; Giustino Parruti; Mauro Giacomini Journal: Int J Environ Res Public Health Date: 2020-01-10 Impact factor: 3.390
Authors: Cassie Cunningham Goedken; Marylou Guihan; Charnetta R Brown; Swetha Ramanathan; Amanda Vivo; Katie J Suda; Margaret A Fitzpatrick; Linda Poggensee; Eli N Perencevich; Michael Rubin; Heather Schacht Reisinger; Martin Evans; Charlesnika T Evans Journal: Implement Sci Commun Date: 2021-06-29
Authors: William E Trick; Michael Y Lin; Robynn Cheng-Leidig; Mary Driscoll; Angela S Tang; Wei Gao; Erica Runningdeer; M Allison Arwady; Robert A Weinstein Journal: Emerg Infect Dis Date: 2015-10 Impact factor: 6.883