Literature DB >> 24600302

Role and implications of nanodiagnostics in the changing trends of clinical diagnosis.

Khalid Khalaf Alharbi1, Yazeed A Al-Sheikh1.   

Abstract

Nanodiagnostics is the term used for the application of nanobiotechnology in molecular diagnosis, which is important for developing personalized cancer therapy. It is usually based on pharmacogenetics, pharmacogenomics, and pharmacoproteomic information but also takes into consideration environmental factors that influence response to therapy. Nanotechnology in medicine involves applications of nanoparticles currently under development, as well as longer range research that involves the use of manufactured nano-robots to make repairs at the cellular level. Nanodiagnostic technologies are also being used to refine the discovery of biomarkers, as nanoparticles offer advantages of high volume/surface ratio and multifunctionality. Biomarkers are important basic components of personalized medicine and are applicable to the management of cancer as well. The field of nano diagnostics raises certain ethical concerns related with the testing of blood. With advances in diagnostic technologies, doctors will be able to give patients complete health checks quickly and routinely. If any medication is required this will be tailored specifically to the individual based on their genetic makeup, thus preventing unwanted side-effects.

Entities:  

Keywords:  DNA sequencing; Nanodiagnostics; PCR

Year:  2013        PMID: 24600302      PMCID: PMC3942856          DOI: 10.1016/j.sjbs.2013.11.001

Source DB:  PubMed          Journal:  Saudi J Biol Sci        ISSN: 2213-7106            Impact factor:   4.219


  43 in total

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Review 4.  Nanotechnology for the biologist.

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Journal:  J Leukoc Biol       Date:  2005-05-27       Impact factor: 4.962

5.  Collagen scaffolds reinforced with biomimetic composite nano-sized carbonate-substituted hydroxyapatite crystals and shaped by rapid prototyping to contain internal microchannels.

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Review 6.  Nano- and microparticle-based imaging of cardiovascular interventions: overview.

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Journal:  Radiology       Date:  2007-05       Impact factor: 11.105

Review 7.  Nanofiber technology: designing the next generation of tissue engineering scaffolds.

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Authors:  Paul Schoenhagen; Jodie L Conyers
Journal:  Recent Pat Cardiovasc Drug Discov       Date:  2008-06

Review 10.  Nanotechnology applications in medicine.

Authors:  Elena Angeli; Renato Buzio; Giuseppe Firpo; Raffaella Magrassi; Valentina Mussi; Luca Repetto; Ugo Valbusa
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  7 in total

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Journal:  Environ Sci Pollut Res Int       Date:  2017-07-31       Impact factor: 4.223

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Authors:  Rajiv Kumar; Bhupender S Chhikara; Kiran Gulia; Mitrabasu Chhillar
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Review 3.  Nanotechnology-Based Surface Plasmon Resonance Affinity Biosensors for In Vitro Diagnostics.

Authors:  Riccarda Antiochia; Paolo Bollella; Gabriele Favero; Franco Mazzei
Journal:  Int J Anal Chem       Date:  2016-08-10       Impact factor: 1.885

Review 4.  Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors.

Authors:  Bilal Zulfiqar; Amnah Mahroo; Kaenat Nasir; Rai Khalid Farooq; Nasir Jalal; Muhammad Usman Rashid; Kashif Asghar
Journal:  Onco Targets Ther       Date:  2017-01-21       Impact factor: 4.147

5.  Development of a portable lab-on-a-valve device for making primary diagnoses based on gold-nanoparticle aggregation induced by a switchable linker.

Authors:  Jungwoo Hahn; Eunghee Kim; Hyebin Han; Young Jin Choi
Journal:  RSC Adv       Date:  2020-08-24       Impact factor: 4.036

Review 6.  Nanotechnology in the Diagnosis and Treatment of Osteomyelitis.

Authors:  Demi Zapata; Jordan Higgs; Hunter Wittholt; Kishore Chittimalli; Amanda E Brooks; Pranothi Mulinti
Journal:  Pharmaceutics       Date:  2022-07-27       Impact factor: 6.525

7.  Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions.

Authors:  Wendy Stevens; Natasha Gous; Nathan Ford; Lesley E Scott
Journal:  BMC Med       Date:  2014-09-08       Impact factor: 8.775

  7 in total

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