Literature DB >> 24599434

Severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis in two Syrian refugee infants: a challenge to differentiate from acute leukaemia.

Burcu Belen1, Burcu Ozturk Hismi, Ulker Kocak.   

Abstract

Megaloblastic anaemia due to vitamin B12 deficiency is rare in childhood. However, as most cases are due to maternal insufficiency, it is mainly seen in breastfed infants especially when the mother's socioeconomic status is low and the nutrition is not adequate. We present case of two Syrian refugee infants with severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis.

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Year:  2014        PMID: 24599434      PMCID: PMC3948160          DOI: 10.1136/bcr-2014-203742

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Current hematological findings in cobalamin deficiency. A study of 201 consecutive patients with documented cobalamin deficiency.

Authors:  E Andrès; S Affenberger; J Zimmer; S Vinzio; D Grosu; G Pistol; F Maloisel; T Weitten; G Kaltenbach; J-F Blicklé
Journal:  Clin Lab Haematol       Date:  2006-02

2.  Severe vitamin B12 deficiency in a breast fed infant with pancytopenia.

Authors:  Funda Erkasar Citak; Elvan Caglar Citak
Journal:  J Trop Pediatr       Date:  2009-07-17       Impact factor: 1.165

3.  A child with vitamin B12 deficiency presenting with pancytopenia and hyperpigmentation.

Authors:  Ozlem Pelin Simşek; Nazli Gönç; Fatma Gümrük; Mualla Cetin
Journal:  J Pediatr Hematol Oncol       Date:  2004-12       Impact factor: 1.289

Review 4.  Nutritional vitamin B12 deficiency in infancy: three case reports and a review of the literature.

Authors:  J J Doyle; A M Langevin; A Zipursky
Journal:  Pediatr Hematol Oncol       Date:  1989       Impact factor: 1.969

5.  Reversible marked splenomegaly in pernicious anemia.

Authors:  R K Pruthi; A Tefferi; R M Petitt
Journal:  Ann Intern Med       Date:  1993-11-15       Impact factor: 25.391

6.  Bone marrow examination of pancytopenic children.

Authors:  Fauzia Shafi Khan; Rabiya Fayyaz Hasan
Journal:  J Pak Med Assoc       Date:  2012-07       Impact factor: 0.781

7.  Pancytopenia due to vitamin B12 deficiency in a breast-fed infant.

Authors:  Idil Yenicesu
Journal:  Pediatr Hematol Oncol       Date:  2008-06       Impact factor: 1.969

8.  Severe vitamin B12 deficiency resulting in pancytopenia, splenomegaly and leukoerythroblastosis.

Authors:  Thorvardur R Halfdanarson; James A Walker; Mark R Litzow; Curtis A Hanson
Journal:  Eur J Haematol       Date:  2008-01-23       Impact factor: 2.997

  8 in total
  3 in total

1.  Severe vitamin B₁₂ deficiency in a 15-year-old boy: presentation with haemolysis and pancytopenia.

Authors:  Ebru Yılmaz Keskin; Mahmut Keskin
Journal:  BMJ Case Rep       Date:  2015-05-14

Review 2.  Pernicious Anemia: The Hematological Presentation of a Multifaceted Disorder Caused by Cobalamin Deficiency.

Authors:  Gianluca Esposito; Ludovica Dottori; Giulia Pivetta; Irene Ligato; Emanuele Dilaghi; Edith Lahner
Journal:  Nutrients       Date:  2022-04-17       Impact factor: 6.706

Review 3.  Missing Cells: Pathophysiology, Diagnosis, and Management of (Pan)Cytopenia in Childhood.

Authors:  Miriam Erlacher; Brigitte Strahm
Journal:  Front Pediatr       Date:  2015-07-13       Impact factor: 3.418

  3 in total

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