Literature DB >> 24599428

Nitrofurantoin immune-mediated drug-induced liver injury: a serious complication of a commonly prescribed medication.

Theresa Hydes1, Mark Wright, Eleanor Jaynes, Kathryn Nash.   

Abstract

Nitrofurantoin is recommended for first line prophylaxis of recurrent urinary tract infections. Despite a number of side effects it is increasingly prescribed due to its high efficacy, low cost and minimal antimicrobial resistance. Nitrofurantoin-induced immune-mediated liver injury is a particularly serious complication, resulting in both acute hepatic failure and cirrhosis with continued use. We describe the course of two patients who recently presented to our hospital in order to highlight this.

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Year:  2014        PMID: 24599428      PMCID: PMC3947996          DOI: 10.1136/bcr-2013-203136

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Drug-induced autoimmune hepatitis: clinical characteristics and prognosis.

Authors:  Einar Björnsson; Jayant Talwalkar; Sombat Treeprasertsuk; Patrick S Kamath; Naoki Takahashi; Schuyler Sanderson; Matthias Neuhauser; Keith Lindor
Journal:  Hepatology       Date:  2010-06       Impact factor: 17.425

2.  Hepatitis due to nitrofurantoin.

Authors:  L C Mollison; P Angus; M Richards; R M Jones; J Ireton
Journal:  Med J Aust       Date:  1992-03-02       Impact factor: 7.738

Review 3.  Long-term hepatic memory for hypersensitivity to nitrofurantoin.

Authors:  L A Paiva; P J Wright; R S Koff
Journal:  Am J Gastroenterol       Date:  1992-07       Impact factor: 10.864

4.  Outcome and prognostic markers in severe drug-induced liver disease.

Authors:  Einar Björnsson; Rolf Olsson
Journal:  Hepatology       Date:  2005-08       Impact factor: 17.425

5.  Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States.

Authors:  Naga Chalasani; Robert J Fontana; Herbert L Bonkovsky; Paul B Watkins; Timothy Davern; Jose Serrano; Hongqiu Yang; James Rochon
Journal:  Gastroenterology       Date:  2008-09-17       Impact factor: 22.682

6.  Hepatic injury associated with the use of nitrofurans: a clinicopathological study of 52 reported cases.

Authors:  B H Stricker; A P Blok; F H Claas; G E Van Parys; V J Desmet
Journal:  Hepatology       Date:  1988 May-Jun       Impact factor: 17.425

  6 in total
  3 in total

1.  Nitrofurantoin-induced liver failure: A fatal yet forgotten complication.

Authors:  Trevor Luk; Brett D Edwards; Duane Bates; Christopher Evernden; Jenny Edwards
Journal:  Can Fam Physician       Date:  2021-05       Impact factor: 3.275

2.  An Unusual Case of Drug-Induced Liver Injury Secondary to Nitrofurantoin Use.

Authors:  Stephen Wonnacott; Dhir Gala; Mili Shah; Diksha Kaul; Vikash Kumar
Journal:  Cureus       Date:  2022-07-15

3.  The protective effect of Esculentoside A on experimental acute liver injury in mice.

Authors:  Fang Zhang; Xingtong Wang; Xiaochen Qiu; Junjie Wang; He Fang; Zhihong Wang; Yu Sun; Zhaofan Xia
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

  3 in total

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