Literature DB >> 24597845

Palladium-catalyzed direct arylation of indoles with cyclohexanones.

Shanping Chen1, Yunfeng Liao, Feng Zhao, Hongrui Qi, Saiwen Liu, Guo-Jun Deng.   

Abstract

A novel palladium catalyzed approach to 3-arylindoles was developed from indoles and cyclohexanones. Various cyclohexanones acted as aryl sources via an alkylation and dehydrogenation sequence using molecular oxygen as the hydrogen acceptor. This method showed good regioselectivity and afforded 3-arylindoles as the sole products.

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Year:  2014        PMID： 24597845     DOI： 10.1021/ol500231c

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

1.  Reductive Cyclization of Halo-Ketones to Form 3-Hydroxy-2-Oxindoles via Palladium Catalyzed Hydrogenation: A Hydrogen-Mediated Grignard Addition.

Authors:  Inji Shin; Stephen D Ramgren; Michael J Krische
Journal:  Tetrahedron       Date:  2015-09-02       Impact factor: 2.457

2.  Palladium-Catalyzed Aerobic Dehydrogenation of Cyclic Hydrocarbons for the Synthesis of Substituted Aromatics and Other Unsaturated Products.

Authors:  Andrei V Iosub; Shannon S Stahl
Journal:  ACS Catal       Date:  2016-10-24       Impact factor: 13.084

3.  Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism.

Authors:  Connor J O'Brien; Daniel G Droege; Alexander Y Jiu; Shivaani S Gandhi; Nick A Paras; Steven H Olson; Jay Conrad
Journal:  J Org Chem       Date:  2018-07-06       Impact factor: 4.354

4.  Palladium-catalyzed aerobic oxidative dehydrogenation of cyclohexenes to substituted arene derivatives.

Authors:  Andrei V Iosub; Shannon S Stahl
Journal:  J Am Chem Soc       Date:  2015-03-09       Impact factor: 15.419

5.  Versatile routes for synthesis of diarylamines through acceptorless dehydrogenative aromatization catalysis over supported gold-palladium bimetallic nanoparticles.

Authors:  Kento Taniguchi; Xiongjie Jin; Kazuya Yamaguchi; Kyoko Nozaki; Noritaka Mizuno
Journal:  Chem Sci       Date:  2016-12-01       Impact factor: 9.825

6.  Formal aromaticity transfer for palladium-catalyzed coupling between phenols and pyrrolidines/indolines.

Authors:  Zihang Qiu; Jiang-Sheng Li; Chao-Jun Li
Journal:  Chem Sci       Date:  2017-08-10       Impact factor: 9.825

7.  Photooxidation of 2-(tert-Butyl)-3-Methyl-2,3,5,6,7,8-Hexahydroquinazolin-4(1H)-one, an Example of Singlet Oxygen ene Reaction.

Authors:  Adrian Méndez; Jonathan Román Valdez-Camacho; Jaime Escalante
Journal:  Molecules       Date:  2020-10-29       Impact factor: 4.411

8.  Unlocking a self-catalytic cycle in a copper-catalyzed aerobic oxidative coupling/cyclization reaction.

Authors:  Jianming Liu; Xiaopei Wang; Zhiyue Wang; Yan Yang; Qinghu Tang; Hongchi Liu; Hanmin Huang
Journal:  iScience       Date:  2022-02-12

9.  Exploration of C-H and N-H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines.

Authors:  Michael Ghobrial; Marko D Mihovilovic; Michael Schnürch
Journal:  Beilstein J Org Chem       Date:  2014-09-15       Impact factor: 2.883
  9 in total

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