Literature DB >> 24597672

Beyond stimulus deprivation: iron deficiency and cognitive deficits in postinstitutionalized children.

Jenalee R Doom1, Megan R Gunnar, Michael K Georgieff, Maria G Kroupina, Kristin Frenn, Anita J Fuglestad, Stephanie M Carlson.   

Abstract

Children adopted from institutions have been studied as models of the impact of stimulus deprivation on cognitive development (Nelson, Bos, Gunnar, & Sonuga-Barke, 2011), but these children may also suffer from micronutrient deficiencies (Fuglestad et al., 2008). The contributions of iron deficiency (ID) and duration of deprivation on cognitive functioning in children adopted from institutions between 17 and 36 months of age were examined. ID was assessed in 55 children soon after adoption, and cognitive functioning was evaluated 11-14.6 months postadoption when the children averaged 37.4 months old (SD = 4.9). ID at adoption and longer duration of institutional care independently predicted lower IQ scores and executive function (EF) performance. IQ did not mediate the association between ID and EF.
© 2014 The Authors. Child Development © 2014 Society for Research in Child Development, Inc.

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Year:  2014        PMID: 24597672      PMCID: PMC4156571          DOI: 10.1111/cdev.12231

Source DB:  PubMed          Journal:  Child Dev        ISSN: 0009-3920


  33 in total

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Authors:  Seth D Pollak; Charles A Nelson; Mary F Schlaak; Barbara J Roeber; Sandi S Wewerka; Kristen L Wiik; Kristin A Frenn; Michelle M Loman; Megan R Gunnar
Journal:  Child Dev       Date:  2010 Jan-Feb

4.  Normality and impairment following profound early institutional deprivation: a longitudinal follow-up into early adolescence.

Authors:  Jana M Kreppner; Michael Rutter; Celia Beckett; Jenny Castle; Emma Colvert; Christine Groothues; Amanda Hawkins; Thomas G O'Connor; Suzanne Stevens; Edmund J S Sonuga-Barke
Journal:  Dev Psychol       Date:  2007-07

5.  Iron deficiency after arrival is associated with general cognitive and behavioral impairment in post-institutionalized children adopted from Eastern Europe.

Authors:  Anita J Fuglestad; Michael K Georgieff; Sandra L Iverson; Bradley S Miller; Anna Petryk; Dana E Johnson; Maria G Kroupina
Journal:  Matern Child Health J       Date:  2013-08

6.  RMediation: an R package for mediation analysis confidence intervals.

Authors:  Davood Tofighi; David P MacKinnon
Journal:  Behav Res Methods       Date:  2011-09

Review 7.  Long-term brain and behavioral consequences of early iron deficiency.

Authors:  Michael K Georgieff
Journal:  Nutr Rev       Date:  2011-11       Impact factor: 7.110

8.  Do theory of mind and executive function deficits underlie the adverse outcomes associated with profound early deprivation?: findings from the English and Romanian adoptees study.

Authors:  Emma Colvert; Michael Rutter; Jana Kreppner; Celia Beckett; Jenny Castle; Christine Groothues; Amanda Hawkins; Suzanne Stevens; Edmund J S Sonuga-Barke
Journal:  J Abnorm Child Psychol       Date:  2008-04-22

9.  The Neurobiological Toll of Early Human Deprivation.

Authors:  Charles A Nelson; Karen Bos; Megan R Gunnar; Edmund J S Sonuga-Barke
Journal:  Monogr Soc Res Child Dev       Date:  2011-12

10.  Is sub-nutrition necessary for a poor outcome following early institutional deprivation?

Authors:  Edmund J S Sonuga-Barke; Celia Beckett; Jana Kreppner; Jenny Castle; Emma Colvert; Suzanne Stevens; Amanda Hawkins; Michael Rutter
Journal:  Dev Med Child Neurol       Date:  2008-09       Impact factor: 5.449

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  15 in total

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Review 2.  The UNC/UMN Baby Connectome Project (BCP): An overview of the study design and protocol development.

Authors:  Brittany R Howell; Martin A Styner; Wei Gao; Pew-Thian Yap; Li Wang; Kristine Baluyot; Essa Yacoub; Geng Chen; Taylor Potts; Andrew Salzwedel; Gang Li; John H Gilmore; Joseph Piven; J Keith Smith; Dinggang Shen; Kamil Ugurbil; Hongtu Zhu; Weili Lin; Jed T Elison
Journal:  Neuroimage       Date:  2018-03-22       Impact factor: 6.556

3.  Executive function and magnitude skills in preschool children.

Authors:  Emily O Prager; Maria D Sera; Stephanie M Carlson
Journal:  J Exp Child Psychol       Date:  2016-04-12

4.  Infant iron deficiency, child affect, and maternal unresponsiveness: Testing the long-term effects of functional isolation.

Authors:  Patricia East; Betsy Lozoff; Estela Blanco; Erin Delker; Jorge Delva; Pamela Encina; Sheila Gahagan
Journal:  Dev Psychol       Date:  2017-09-21

5.  Associations Among Infant Iron Deficiency, Childhood Emotion and Attention Regulation, and Adolescent Problem Behaviors.

Authors:  Patricia East; Erin Delker; Betsy Lozoff; Jorge Delva; Marcela Castillo; Sheila Gahagan
Journal:  Child Dev       Date:  2017-02-23

6.  Striking while the iron is hot: Understanding the biological and neurodevelopmental effects of iron deficiency to optimize intervention in early childhood.

Authors:  Jenalee R Doom; Michael K Georgieff
Journal:  Curr Pediatr Rep       Date:  2014-12-01

7.  Rapid Infant Prefrontal Cortex Development and Sensitivity to Early Environmental Experience.

Authors:  Amanda S Hodel
Journal:  Dev Rev       Date:  2018-03-11

8.  Executive Function in Previously Institutionalized Children.

Authors:  Emily C Merz; Katia M Harlé; Kimberly G Noble; Robert B McCall
Journal:  Child Dev Perspect       Date:  2016-02-19

9.  Executive functioning deficits in preschool children with Fetal Alcohol Spectrum Disorders.

Authors:  Anita J Fuglestad; Marisa L Whitley; Stephanie M Carlson; Christopher J Boys; Judith K Eckerle; Birgit A Fink; Jeffrey R Wozniak
Journal:  Child Neuropsychol       Date:  2014-07-11       Impact factor: 2.500

10.  Institutional care and iron deficiency increase ADHD symptomology and lower IQ 2.5-5 years post-adoption.

Authors:  Jenalee R Doom; Michael K Georgieff; Megan R Gunnar
Journal:  Dev Sci       Date:  2014-07-28
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