R M Sandi1, K G Pol2, P Basavaraj3, Nitin Khuller4, Shilpi Singh5. 1. Reader, Department of Periodontics, Yerala Medical Trust's Dental College & Hospital , Navi Mumbai-410210 Maharashtra, India . 2. Lecturer, Department of Periodontics Yerala Medical Trust's Dental College & Hospital , Navi Mumbai-410210 Maharashtra, India . 3. Professor & Head, Department of Public Health Dentistry, DJ College of Dental Sciences & Research , Modinagar, U.P., India . 4. Reader, Department of Periodontics, Swami Devi Dayal Hospital & Dental College , Golpura, Barwala, Panchkula, Haryana, India . 5. Senior Lecturer, Department of Public Health Dentistry, DJ College of Dental Sciences & Research , Modinagar, U.P., India .
Abstract
PURPOSE: To assess serum cholesterol, triglycerides, high and low density lipoprotein (HDL and LDL) levels (serum lipid profile) in subjects with chronic periodontitis and the possible association for risk of cardiovascular disease (CVD). MATERIALS AND METHODS: Total of 80 participants (42 males and 38 females) who were in the age range of 30-65 years were divided into test group (group I- 40 subjects with chronic periodontitis) and control group (group II- 40 subjects with healthy periodontium), based on their periodontal disease statuses. Three ml of venous blood samples were taken for measurement of parameters of lipid metabolism [serum cholesterol (chol); triglycerides (Tg); HDL and LDL. RESULTS: Significant increase in serum cholesterol and LDL (P<0.05) were observed in test group (group I), whereas serum triglycerides and HDL (P>0.66) showed no significant increase in test group (group I) as compared to their values in the control group (group II). A P-value of < 0.05 was considered for statistical significance. CONCLUSIONS: Subjects with chronic periodontitis showed increased serum cholesterol and LDL levels. This may suggest that these subjects are potentially at a risk of getting CVD.
PURPOSE: To assess serum cholesterol, triglycerides, high and low density lipoprotein (HDL and LDL) levels (serum lipid profile) in subjects with chronic periodontitis and the possible association for risk of cardiovascular disease (CVD). MATERIALS AND METHODS: Total of 80 participants (42 males and 38 females) who were in the age range of 30-65 years were divided into test group (group I- 40 subjects with chronic periodontitis) and control group (group II- 40 subjects with healthy periodontium), based on their periodontal disease statuses. Three ml of venous blood samples were taken for measurement of parameters of lipid metabolism [serum cholesterol (chol); triglycerides (Tg); HDL and LDL. RESULTS: Significant increase in serum cholesterol and LDL (P<0.05) were observed in test group (group I), whereas serum triglycerides and HDL (P>0.66) showed no significant increase in test group (group I) as compared to their values in the control group (group II). A P-value of < 0.05 was considered for statistical significance. CONCLUSIONS: Subjects with chronic periodontitis showed increased serum cholesterol and LDL levels. This may suggest that these subjects are potentially at a risk of getting CVD.
Authors: Tuomas Saxlin; Liisa Suominen-Taipale; Anna Kattainen; Jukka Marniemi; Matti Knuuttila; Pekka Ylöstalo Journal: J Clin Periodontol Date: 2008-12 Impact factor: 8.728
Authors: Joanna Maciąg; Grzegorz Osmenda; Daniel Nowakowski; Grzegorz Wilk; Anna Maciąg; Tomasz Mikołajczyk; Ryszard Nosalski; Agnieszka Sagan; Magdalena Filip; Mirosław Dróżdż; Jolanta Loster; Tomasz J Guzik; Marta Cześnikiewicz-Guzik Journal: Biomed Res Int Date: 2014-06-19 Impact factor: 3.411