Literature DB >> 24595483

[Osteomyelitis in adults: in consideration of soft tissue problems].

D Behrendt1, C Josten.   

Abstract

Osteomyelitis in the adult is a rare disease. In this review we present the diagnostic and therapeutic principles for treatment of chronic osteomyelitis of long bones in adults. The most important step in treating osteomyelitis is the detection of the offending bacteria. The diagnostics should be performed with tissue and fluids from the depth of the wound. Superficial samples and swaps from fistulas should not be used to determine the offending bacteria. The defining criteria of chronic osteomyelitis are necrotic and non vascularized bony tissue. The appropriate therapy includes radical excision of the diseased bone and infected scar tissue, closure of the wound with well vascularized tissue including (muscle) flaps, stabilization of instable situations by external fixation and administration of adequate antibiotics. Remaining necrotic bone tissue is one of the most relevant sources for recurrent infection.

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Year:  2014        PMID: 24595483     DOI: 10.1007/s00104-012-2393-8

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  30 in total

Review 1.  Treatment of infections associated with surgical implants.

Authors:  Rabih O Darouiche
Journal:  N Engl J Med       Date:  2004-04-01       Impact factor: 91.245

Review 2.  Biofilm theory can guide the treatment of device-related orthopaedic infections.

Authors:  J William Costerton
Journal:  Clin Orthop Relat Res       Date:  2005-08       Impact factor: 4.176

Review 3.  The management of open fractures.

Authors:  R B Gustilo; R L Merkow; D Templeman
Journal:  J Bone Joint Surg Am       Date:  1990-02       Impact factor: 5.284

4.  Reconstruction of segmental bone defects due to chronic osteomyelitis with use of an external fixator and an intramedullary nail.

Authors:  Mehmet Kocaoglu; Levent Eralp; Haroon Ur Rashid; Cengiz Sen; Kerem Bilsel
Journal:  J Bone Joint Surg Am       Date:  2006-10       Impact factor: 5.284

Review 5.  Treating osteomyelitis: antibiotics and surgery.

Authors:  Nalini Rao; Bruce H Ziran; Benjamin A Lipsky
Journal:  Plast Reconstr Surg       Date:  2011-01       Impact factor: 4.730

6.  Introduction to adult posttraumatic osteomyelitis of the tibia.

Authors:  P D Holtom; A M Smith
Journal:  Clin Orthop Relat Res       Date:  1999-03       Impact factor: 4.176

7.  Chronic osteomyelitis. The effect of the extent of surgical resection on infection-free survival.

Authors:  A H Simpson; M Deakin; J M Latham
Journal:  J Bone Joint Surg Br       Date:  2001-04

8.  Diagnostic value of sinus-tract cultures in chronic osteomyelitis.

Authors:  P A Mackowiak; S R Jones; J W Smith
Journal:  JAMA       Date:  1978-06-30       Impact factor: 56.272

9.  The incidence of osteitis in open fractures: an analysis of 948 open fractures (a review of the Hannover experience).

Authors:  N P Suedkamp; N Barbey; A Veuskens; A Tempka; N P Haas; R Hoffmann; H Tscherne
Journal:  J Orthop Trauma       Date:  1993       Impact factor: 2.512

10.  Osteomyelitis in grade II and III open tibia fractures with late debridement.

Authors:  K Kindsfater; E A Jonassen
Journal:  J Orthop Trauma       Date:  1995-04       Impact factor: 2.512

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