Yuexiang Wang1, Anika Filius1, Chunfeng Zhao1, Sandra M Passe1, Andrew R Thoreson1, Kai-Nan An1, Peter C Amadio2. 1. Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, 200 1st St SW, Rochester, MN 55905; Tendon and Soft Tissue Biology Laboratory, Division of Orthopedic Research, Mayo Clinic, Rochester, MN. 2. Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, 200 1st St SW, Rochester, MN 55905; Tendon and Soft Tissue Biology Laboratory, Division of Orthopedic Research, Mayo Clinic, Rochester, MN. Electronic address: pamadio@mayo.edu.
Abstract
RATIONALE AND OBJECTIVES: Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome. Strong pinch or grip with wrist flexion has been considered a risk factor for CTS. Studying median nerve displacement during wrist movements may provide useful information about median nerve kinematic changes in patients with CTS. The purpose of this study was to evaluate the deformability and mobility of the median nerve in patients with CTS compared to healthy subjects. MATERIALS AND METHODS: Dynamic ultrasound images were obtained in 20 affected wrists of 13 patients with CTS. Results were compared to complementary data obtained from both wrists of 10 healthy subjects reported in a previous study. Shape and position of initial and final median nerve were measured and analyzed for six defined wrist movements. The deformation ratios for each movement were defined as the median nerve area, perimeter, and circularity of the final position normalized by respective values assessed in the initial position. The median nerve displacement vector and magnitude were also calculated. RESULTS: The deformation ratio for circularity was significantly less in patients with CTS compared to healthy subjects during wrist flexion (P < .05). The mean vector of median nerve displacement during wrist flexion was significantly different between patients with CTS and healthy subjects (P < .05). The displacement magnitude of the median nerve was found to be less in patients with CTS compared to healthy subjects during most movements, with the exception of wrist extension with fingers extended. CONCLUSIONS: Patients with CTS differ from normal subjects with regard to mobility and deformability of the median nerve.
RATIONALE AND OBJECTIVES:Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome. Strong pinch or grip with wrist flexion has been considered a risk factor for CTS. Studying median nerve displacement during wrist movements may provide useful information about median nerve kinematic changes in patients with CTS. The purpose of this study was to evaluate the deformability and mobility of the median nerve in patients with CTS compared to healthy subjects. MATERIALS AND METHODS: Dynamic ultrasound images were obtained in 20 affected wrists of 13 patients with CTS. Results were compared to complementary data obtained from both wrists of 10 healthy subjects reported in a previous study. Shape and position of initial and final median nerve were measured and analyzed for six defined wrist movements. The deformation ratios for each movement were defined as the median nerve area, perimeter, and circularity of the final position normalized by respective values assessed in the initial position. The median nerve displacement vector and magnitude were also calculated. RESULTS: The deformation ratio for circularity was significantly less in patients with CTS compared to healthy subjects during wrist flexion (P < .05). The mean vector of median nerve displacement during wrist flexion was significantly different between patients with CTS and healthy subjects (P < .05). The displacement magnitude of the median nerve was found to be less in patients with CTS compared to healthy subjects during most movements, with the exception of wrist extension with fingers extended. CONCLUSIONS:Patients with CTS differ from normal subjects with regard to mobility and deformability of the median nerve.
Authors: Verena J M M Schrier; Stefanie Evers; Jennifer R Geske; Walter K Kremers; Hector R Villarraga; Ruud W Selles; Steven E R Hovius; Russell Gelfman; Peter C Amadio Journal: Ultrasound Med Biol Date: 2020-06-26 Impact factor: 2.998
Authors: Stefanie Evers; Andrew R Thoreson; Jay Smith; Chunfeng Zhao; Jennifer R Geske; Peter C Amadio Journal: Muscle Nerve Date: 2017-07-06 Impact factor: 3.217
Authors: Mohammad Hosseini-Farid; Verena J M M Schrier; Julia Starlinger; Peter C Amadio Journal: J Ultrasound Med Date: 2020-10-19 Impact factor: 2.153
Authors: Verena J M M Schrier; Stefanie Evers; Jennifer R Geske; Walter K Kremers; Hector R Villarraga; Sanjeev Kakar; Ruud W Selles; Steven E R Hovius; Russell Gelfman; Peter C Amadio Journal: Ultrasound Med Biol Date: 2019-09-02 Impact factor: 2.998
Authors: Anika Filius; Marjan Scheltens; Hans G Bosch; Pieter A van Doorn; Henk J Stam; Steven E R Hovius; Peter C Amadio; Ruud W Selles Journal: J Orthop Res Date: 2015-05-07 Impact factor: 3.494