OBJECTIVE: To compare the levels of ceruloplasmin (cp) in the amniotic fluids and maternal bloods of second trimester fetuses with and without neural tube defects (NTD). MATERIALS AND METHODS: 66 pregnant women were included in the study. Amniocentesis was performed in 32 women in a patient group diagnosed as NTD or anencephaly and 34 pregnants in a control group with positive Down Syndrome screening test. Maternal bloods were also taken. Cp was measured with Erel's ceruloplasmin measurement method. RESULTS: The cp levels of the amniotic fluid of patients and controls were not statistically different (p>0.05). The cp levels of the maternal bloods were not different in two groups (p>0.05). CONCLUSION: As an antioxidant, no relation was found between cp and NTD.
OBJECTIVE: To compare the levels of ceruloplasmin (cp) in the amniotic fluids and maternal bloods of second trimester fetuses with and without neural tube defects (NTD). MATERIALS AND METHODS: 66 pregnant women were included in the study. Amniocentesis was performed in 32 women in a patient group diagnosed as NTD or anencephaly and 34 pregnants in a control group with positive Down Syndrome screening test. Maternal bloods were also taken. Cp was measured with Erel's ceruloplasmin measurement method. RESULTS: The cp levels of the amniotic fluid of patients and controls were not statistically different (p>0.05). The cp levels of the maternal bloods were not different in two groups (p>0.05). CONCLUSION: As an antioxidant, no relation was found between cp and NTD.
Authors: Alejandra Pelsman; Carlos Hoyo-Vadillo; Tatiana A Gudasheva; Sergei B Seredenin; Rita U Ostrovskaya; Jorge Busciglio Journal: Int J Dev Neurosci Date: 2003-05 Impact factor: 2.457