Literature DB >> 2459047

Variable-region sequence homologies of human kappa-chains with idiotypic serologic similarities.

H S Kim1, H F Deutsch.   

Abstract

An antibody to the V-region of a kappa I light chain has been used to detect other human kappa-chains with similar idiotypic specificities that appear to be related to complementarity-determining regions (CDR). Four such proteins, three of which react with this antibody, have been sequenced. While the proteins show relatively strong sequence similarities in their CDR2 regions, the relatively high degree of homology in a localized segment of the V-region of lambda-chains detected by this method was not observed here.

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Year:  1988        PMID： 2459047      PMCID： PMC1384975     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  20 in total

1.  Some sequence similarities among cloned mouse DNA segments that code for lambda and kappa light chains of immunoglobulins.

Authors:  T T Wu; E A Kabat; H Bilofsky
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

2.  [Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of the kappa-type, subgroup I (Bence-Jones protein Au)].

Authors:  H Schiechl; N Hilschmann
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1972-03

3.  Relationships of two light chain immunoglobulins isolated from the same human source (low molecular weight immunoglobins).

Authors:  H F Deutsch
Journal:  Immunochemistry       Date:  1965-09

4.  Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac.

Authors:  O Smithies; D Gibson; E M Fanning; R M Goodfliesh; J G Gilman; D L Ballantyne
Journal:  Biochemistry       Date:  1971-12-21       Impact factor: 3.162

5.  The covalent structure of a human gamma G-immunoglobulin. VI. Amino acid sequence of the light chain.

Authors:  P D Gottlieb; B A Cunningham; U Rutishauser; G M Edelman
Journal:  Biochemistry       Date:  1970-08-04       Impact factor: 3.162

6.  The variable region of human immunoglobulins. I. Serologic and structural correlations of antigenic markers common to V lambda I and V lambda IV proteins (isotypic cross-reactivities).

Authors:  L Rivat-Peran; F W Tischendorf; S M Dumitresco; C Rivat; M M Tischendorf; H Haas; H F Deutsch
Journal:  J Immunol       Date:  1980-07       Impact factor: 5.422

7.  Primary structure of kappa light chain from a human myeloma protein.

Authors:  C P Milstein; E V Deverson
Journal:  Eur J Biochem       Date:  1974-11-15

8.  The V region sequence of lambda Bence-Jones protein Wh: evidence for separate germ-line sets within lambda-subgroups.

Authors:  C R Kiefer; H M Patton; B S McGuire; F A Garver
Journal:  J Immunol       Date:  1980-01       Impact factor: 5.422

9.  N-(beta-Iodoethyl)trifluoroacetamide: a new reagent for the aminoethylation of thio groups in proteins.

Authors:  W E Schwartz; P K Smith; G P Royer
Journal:  Anal Biochem       Date:  1980-07-15       Impact factor: 3.365

10.  Evidence supporting somatic assembly of the DNA segments (minigenes), coding for the framework, and complementarity-determining segments of immunoglobulin variable regions.

Authors:  E A Kabat; T T Wu; H Bilofsky
Journal:  J Exp Med       Date:  1979-06-01       Impact factor: 14.307
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