Literature DB >> 24590123

Multiplex detection of nucleic acids using a low cost microfluidic chip and a personal glucose meter at the point-of-care.

Qing Wang1, Hui Wang, Xiaohai Yang, Kemin Wang, Fang Liu, Qing Zhao, Pei Liu, Rongjuan Liu.   

Abstract

A simple assay for multiplex DNA detection has been developed using a microfluidic chip and a personal glucose meter. By using this system, multiplex detection of three genotypes of hepatitis B virus DNA was possible with a detection limit of 10 pM. This point-of-care assay represented a versatile platform for sensitive multiplex target detection.

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Year:  2014        PMID： 24590123     DOI： 10.1039/c4cc00133h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Dose-Dependent Response of Personal Glucose Meters to Nicotinamide Coenzymes: Applications to Point-of-Care Diagnostics of Many Non-Glucose Targets in a Single Step.

Authors:  Jingjing Zhang; Yu Xiang; Miao Wang; Ananda Basu; Yi Lu
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-23       Impact factor: 15.336

2.  Translating in vitro diagnostics from centralized laboratories to point-of-care locations using commercially-available handheld meters.

Authors:  JingJing Zhang; Tian Lan; Yi Lu
Journal:  Trends Analyt Chem       Date:  2019-12-23       Impact factor: 12.296

Review 3.  Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health.

Authors:  Tian Lan; Jingjing Zhang; Yi Lu
Journal:  Biotechnol Adv       Date:  2016-03-03       Impact factor: 14.227

Review 4.  Molecular oncology testing in resource-limited settings.

Authors:  Margaret L Gulley; Douglas R Morgan
Journal:  J Mol Diagn       Date:  2014-09-19       Impact factor: 5.568

5.  Design, Synthesis, and Characterization of Small-Molecule Reagents That Cooperatively Provide Dual Readouts for Triaging and, When Necessary, Quantifying Point-of-Need Enzyme Assays.

Authors:  Adam D Brooks; Hemakesh Mohapatra; Scott T Phillips
Journal:  J Org Chem       Date:  2015-10-16       Impact factor: 4.354

6.  DNAzyme Amplified Aptasensing Platform for Ochratoxin A Detection Using a Personal Glucose Meter.

Authors:  Songbai Zhang; Yunxia Luan; Mengyi Xiong; Jingjing Zhang; Ryan Lake; Yi Lu
Journal:  ACS Appl Mater Interfaces       Date:  2021-02-08       Impact factor: 10.383

7.  A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers.

Authors:  Yan Du; Randall A Hughes; Sanchita Bhadra; Yu Sherry Jiang; Andrew D Ellington; Bingling Li
Journal:  Sci Rep       Date:  2015-06-08       Impact factor: 4.379

Review 8.  A Critical Review of Electrochemical Glucose Sensing: Evolution of Biosensor Platforms Based on Advanced Nanosystems.

Authors:  Vuslat B Juska; Martyn E Pemble
Journal:  Sensors (Basel)       Date:  2020-10-23       Impact factor: 3.576
  8 in total

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