Literature DB >> 24590025

A case of pulmonary hemorrhage due to drug-induced pneumonitis secondary to ticagrelor therapy.

Timothy J Whitmore1, John P O'Shea2, Diana Starac3, Mark G Edwards4, Grant W Waterer5.   

Abstract

We report a case of significant pulmonary hemorrhage developing shortly after commencing ticagrelor and aspirin therapy and requiring coronary artery bypass grafting to safely cease the antiplatelet therapy. Lung biopsy findings were consistent with drug-induced lung injury. Clinicians should be aware of this significant adverse event with this drug class.

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Year:  2014        PMID: 24590025     DOI: 10.1378/chest.13-1502

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  5 in total

1.  Ticagrelor-induced pneumonitis and subsequent pulmonary hemorrhage; drug rash with eosinophilia due to boceprevir; hepatitis C reactivation after starting infliximab; hydralazine-associated immune glomerulonephritis; fluoroquinolones and retinal detachment.

Authors:  Michael A Mancano
Journal:  Hosp Pharm       Date:  2014-06

2.  Efficacy and safety of different doses of tirofiban combined with ticagrelor on diabetic patients with AMI receiving in emergency percutaneous coronary intervention (PCI).

Authors:  Yang Liu; Hengliang Liu; Zhenxuan Hao; Guoying Geng; Qi Chen; Wenjie Han; Kailong Jia; Yuxin Zhou
Journal:  Int J Clin Exp Med       Date:  2015-07-15

3.  Diffuse alveolar hemorrhage associated with ticagrelor therapy after percutaneous coronary intervention.

Authors:  Samet Yılmaz; Oğuz Kılıç; Yalın Tolga Yaylalı
Journal:  Anatol J Cardiol       Date:  2018-07       Impact factor: 1.596

4.  A Case of Diffuse Alveolar Hemorrhage as a Possible Complication of Bivalirudin Therapy.

Authors:  Htun Latt; Sammy Aung; Kyaw Kyaw; Thein Tun Aung; Chanwit Roongsritong
Journal:  Am J Case Rep       Date:  2017-10-10

5.  Ticagrelor Removal From Human Blood.

Authors:  George O Angheloiu; Gabriel B Gugiu; Cristian Ruse; Rishikesh Pandey; Ramachandra R Dasari; Carl Whatling
Journal:  JACC Basic Transl Sci       Date:  2017-04-24
  5 in total

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