C Bes1, B Altunrende2, Ş Yılmaz Türkoğlu2, N Yıldız2, M Soy3. 1. Department of Rheumatology Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul. 2. Department of Neurology, The Hospital of University of Abant Izzet Baysal, Bolu. 3. Department of Rheumatology, Hisar Intercontinental Hospital, İstanbul, Turkey.
Abstract
OBJECTIVE: The incidences of extrapyramidal symptoms and Parkinson's disease were reported to be increased in patients with rheumatoid arthritis (RA). In this study we aimed to explore the frequency of the symptoms of Parkinsonism among RA patients older than 60 years. PATIENTS AND METHODS: 30 (6 males, 24 females) consecutive RA patients, followed at a rheumatology outpatient clinic, who were 60 years of age or older; 23 patients who were diagnosed as PD and 50 sex and age matched healthy controls were included to the study. All participants were examined for the motor and non-motor findings of Parkinsonism including bradykinesia, rigidity, tremor, postural abnormality, upper limb sway abnormality, gait impairment, decrease in facial expression, seborrhea, slowing of speech and impairment in the self care. RESULTS: When the RA, PD cases and healthy control group were compared for bradykinesia, rigidity, tremor, posture, upper limb sway, gait impairment, facial expression, seborrhea, speech and self care; highly significant differences were seen for all parameters. Two out of the 30 RA cases (6,7%) were diagnosed as Parkinson's disease. CONCLUSIONS: The signs of Parkinsonism and Parkinson's disease were found more frequent in elderly RA cases as compared to healthy controls.
OBJECTIVE: The incidences of extrapyramidal symptoms and Parkinson's disease were reported to be increased in patients with rheumatoid arthritis (RA). In this study we aimed to explore the frequency of the symptoms of Parkinsonism among RApatients older than 60 years. PATIENTS AND METHODS: 30 (6 males, 24 females) consecutive RApatients, followed at a rheumatology outpatient clinic, who were 60 years of age or older; 23 patients who were diagnosed as PD and 50 sex and age matched healthy controls were included to the study. All participants were examined for the motor and non-motor findings of Parkinsonism including bradykinesia, rigidity, tremor, postural abnormality, upper limb sway abnormality, gait impairment, decrease in facial expression, seborrhea, slowing of speech and impairment in the self care. RESULTS: When the RA, PD cases and healthy control group were compared for bradykinesia, rigidity, tremor, posture, upper limb sway, gait impairment, facial expression, seborrhea, speech and self care; highly significant differences were seen for all parameters. Two out of the 30 RA cases (6,7%) were diagnosed as Parkinson's disease. CONCLUSIONS: The signs of Parkinsonism and Parkinson's disease were found more frequent in elderly RA cases as compared to healthy controls.
Authors: Atallah F Ahmed; Zhi-Hong Wen; Ahmed H Bakheit; Omer A Basudan; Hazem A Ghabbour; Abdullah Al-Ahmari; Chien-Wei Feng Journal: Plants (Basel) Date: 2022-02-27