Literature DB >> 24589717

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.

Juan Carlos Almagro1, Gary L Gilliland2, Felix Breden3, Jamie K Scott3, Devin Sok4, Matthias Pauthner4, Janice M Reichert5, Gustavo Helguera6, Raiees Andrabi4, Robert Mabry7, Mathieu Bléry8, James E Voss4, Juha Laurén9, Lubna Abuqayyas10, Stefan Barghorn11, Eshel Ben-Jacob12, James E Crowe13, James S Huston14, Stephen Albert Johnston15, Eric Krauland7, Fridtjof Lund-Johansen16, Wayne A Marasco17, Paul W H I Parren18, Kai Y Xu19.   

Abstract

The 24th Antibody Engineering & Therapeutics meeting brought together a broad range of participants who were updated on the latest advances in antibody research and development. Organized by IBC Life Sciences, the gathering is the annual meeting of The Antibody Society, which serves as the scientific sponsor. Preconference workshops on 3D modeling and delineation of clonal lineages were featured, and the conference included sessions on a wide variety of topics relevant to researchers, including systems biology; antibody deep sequencing and repertoires; the effects of antibody gene variation and usage on antibody response; directed evolution; knowledge-based design; antibodies in a complex environment; polyreactive antibodies and polyspecificity; the interface between antibody therapy and cellular immunity in cancer; antibodies in cardiometabolic medicine; antibody pharmacokinetics, distribution and off-target toxicity; optimizing antibody formats for immunotherapy; polyclonals, oligoclonals and bispecifics; antibody discovery platforms; and antibody-drug conjugates.

Entities:  

Keywords:  antibody therapeutics,; antibody-drug conjugate; bispecific antibodies; protein scaffolds

Mesh:

Substances:

Year:  2014        PMID: 24589717      PMCID: PMC4011904          DOI: 10.4161/mabs.28421

Source DB:  PubMed          Journal:  MAbs        ISSN: 1942-0862            Impact factor:   5.857


  150 in total

1.  PIGS: automatic prediction of antibody structures.

Authors:  Paolo Marcatili; Alessandra Rosi; Anna Tramontano
Journal:  Bioinformatics       Date:  2008-07-19       Impact factor: 6.937

Review 2.  Macromolecular modeling with rosetta.

Authors:  Rhiju Das; David Baker
Journal:  Annu Rev Biochem       Date:  2008       Impact factor: 23.643

3.  Using multifocal plane microscopy to reveal novel trafficking processes in the recycling pathway.

Authors:  Zhuo Gan; Sripad Ram; Raimund J Ober; E Sally Ward
Journal:  J Cell Sci       Date:  2013-01-23       Impact factor: 5.285

4.  Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection.

Authors:  Carlos E Milla; James F Chmiel; Frank J Accurso; Donald R VanDevanter; Michael W Konstan; Geoffrey Yarranton; David E Geller
Journal:  Pediatr Pulmonol       Date:  2013-09-09

5.  Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.

Authors:  Florian Klein; Ron Diskin; Johannes F Scheid; Christian Gaebler; Hugo Mouquet; Ivelin S Georgiev; Marie Pancera; Tongqing Zhou; Reha-Baris Incesu; Brooks Zhongzheng Fu; Priyanthi N P Gnanapragasam; Thiago Y Oliveira; Michael S Seaman; Peter D Kwong; Pamela J Bjorkman; Michel C Nussenzweig
Journal:  Cell       Date:  2013-03-28       Impact factor: 41.582

Review 6.  Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies.

Authors:  Peter D Kwong; John R Mascola
Journal:  Immunity       Date:  2012-09-21       Impact factor: 31.745

7.  Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1.

Authors:  Miroslaw K Gorny; Xiao-Hong Wang; Constance Williams; Barbara Volsky; Kathy Revesz; Bradley Witover; Sherri Burda; Mateusz Urbanski; Phillipe Nyambi; Chavdar Krachmarov; Abraham Pinter; Susan Zolla-Pazner; Arthur Nadas
Journal:  Mol Immunol       Date:  2008-10-25       Impact factor: 4.407

8.  Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase.

Authors:  Anton Glieder; Edgardo T Farinas; Frances H Arnold
Journal:  Nat Biotechnol       Date:  2002-10-07       Impact factor: 54.908

Review 9.  Accelerating next-generation vaccine development for global disease prevention.

Authors:  Wayne C Koff; Dennis R Burton; Philip R Johnson; Bruce D Walker; Charles R King; Gary J Nabel; Rafi Ahmed; Maharaj K Bhan; Stanley A Plotkin
Journal:  Science       Date:  2013-05-31       Impact factor: 47.728

Review 10.  A Blueprint for HIV Vaccine Discovery.

Authors:  Dennis R Burton; Rafi Ahmed; Dan H Barouch; Salvatore T Butera; Shane Crotty; Adam Godzik; Daniel E Kaufmann; M Juliana McElrath; Michel C Nussenzweig; Bali Pulendran; Chris N Scanlan; William R Schief; Guido Silvestri; Hendrik Streeck; Bruce D Walker; Laura M Walker; Andrew B Ward; Ian A Wilson; Richard Wyatt
Journal:  Cell Host Microbe       Date:  2012-10-18       Impact factor: 21.023

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  2 in total

1.  Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys.

Authors:  Lise I Loberg; Meha Chhaya; Alexander Ibraghimov; Edit Tarcsa; Andreas Striebinger; Andreas Popp; Lili Huang; Frank Oellien; Stefan Barghorn
Journal:  MAbs       Date:  2021 Jan-Dec       Impact factor: 5.857

2.  Large-Scale Gastric Cancer Susceptibility Gene Identification Based on Gradient Boosting Decision Tree.

Authors:  Qing Chen; Ji Zhang; Banghe Bao; Fan Zhang; Jie Zhou
Journal:  Front Mol Biosci       Date:  2022-01-13
  2 in total

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