OBJECTIVE: The primary purpose of the study was to determine whether Multisystemic Therapy adapted for health care settings (MST-HC) improved asthma management and health outcomes in high-risk African American adolescents with asthma. METHOD: Eligibility included self-reported African American ethnicity, ages 12 to 16, moderate to severe asthma, and an inpatient hospitalization or at least 2 emergency department visits for asthma in the last 12 months. Adolescents and their families (N = 170) were randomized to MST-HC or in-home family support. Data were collected at baseline and posttreatment (7 months) based on an asthma management interview, medication adherence phone diary, and lung function biomarker (forced expiratory volume in 1 s [FEV1]). Analyses were conducted using linear mixed modeling for continuous outcomes and generalized linear mixed modeling for binary outcomes. RESULTS: In intent-to-treat analyses, adolescents randomized to MST-HC were more likely to improve on 2 of the measures of medication adherence and FEV1. Per-protocol analysis demonstrated that MST-HC had a medium effect on adherence measures and had a small to medium effect on lung function and the adolescent's response to asthma exacerbations. CONCLUSION: There are few interventions that have been shown to successfully improve asthma management in minority youth at highest risk for poor morbidity and mortality. MST, a home-based psychotherapy originally developed to target behavior problems in youth, improved asthma management and lung function compared to a strong comparison condition. Further follow-up is necessary to determine whether MST-HC reduces health care utilization accounting for seasonal variability. A limitation to the study is that a greater number of participants in the control group came from single-parent families than in the MST group. PsycINFO Database Record (c) 2014 APA, all rights reserved.
OBJECTIVE: The primary purpose of the study was to determine whether Multisystemic Therapy adapted for health care settings (MST-HC) improved asthma management and health outcomes in high-risk African American adolescents with asthma. METHOD: Eligibility included self-reported African American ethnicity, ages 12 to 16, moderate to severe asthma, and an inpatient hospitalization or at least 2 emergency department visits for asthma in the last 12 months. Adolescents and their families (N = 170) were randomized to MST-HC or in-home family support. Data were collected at baseline and posttreatment (7 months) based on an asthma management interview, medication adherence phone diary, and lung function biomarker (forced expiratory volume in 1 s [FEV1]). Analyses were conducted using linear mixed modeling for continuous outcomes and generalized linear mixed modeling for binary outcomes. RESULTS: In intent-to-treat analyses, adolescents randomized to MST-HC were more likely to improve on 2 of the measures of medication adherence and FEV1. Per-protocol analysis demonstrated that MST-HC had a medium effect on adherence measures and had a small to medium effect on lung function and the adolescent's response to asthma exacerbations. CONCLUSION: There are few interventions that have been shown to successfully improve asthma management in minority youth at highest risk for poor morbidity and mortality. MST, a home-based psychotherapy originally developed to target behavior problems in youth, improved asthma management and lung function compared to a strong comparison condition. Further follow-up is necessary to determine whether MST-HC reduces health care utilization accounting for seasonal variability. A limitation to the study is that a greater number of participants in the control group came from single-parent families than in the MST group. PsycINFO Database Record (c) 2014 APA, all rights reserved.
Authors: Charles Glisson; Sonja K Schoenwald; Anthony Hemmelgarn; Philip Green; Denzel Dukes; Kevin S Armstrong; Jason E Chapman Journal: J Consult Clin Psychol Date: 2010-08
Authors: Deborah A Ellis; Sylvie Naar-King; Phillippe B Cunningham; Elizabeth Secord Journal: AIDS Patient Care STDS Date: 2006-02 Impact factor: 5.078
Authors: Giselle S Mosnaim; Andrea A Pappalardo; Scott E Resnick; Christopher D Codispoti; Sindhura Bandi; Lisa Nackers; Rabia N Malik; Vimala Vijayaraghavan; Elizabeth B Lynch; Lynda H Powell Journal: J Allergy Clin Immunol Pract Date: 2015-11-07
Authors: David A Fedele; Andrew McConville; J Graham Thomas; Elizabeth L McQuaid; David M Janicke; Elise M Turner; Jon Moon; Mutasim Abu-Hasan Journal: Contemp Clin Trials Date: 2017-10-03 Impact factor: 2.226