| Literature DB >> 2458835 |
A Kenani1, G Lamblin, J P Hénichart.
Abstract
In order to elucidate the biological role of the sugar residue of the antitumor drug bleomycin, this was deglycosylated by beta-elimination under mild alkaline conditions, and by solvolysis with hydrogen fluoride. The latter procedure proved to be better because it led to the complete deglycosylation without modification of the peptide, thus allowing further biological investigations of this component.Entities:
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Year: 1988 PMID： 2458835 DOI： 10.1016/0008-6215(88)85043-2
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104