Lei Pan1, Peifang Zhang2, Qingshui Yin3. 1. Department of Orthopaedics Surgery, The People's Hospital of Foshan, Sanshui District, Foshan 528100, Guangdong Province, China. 2. Department of Respiratory Medicine, The First People's Hospital of Foshan, Foshan 528000, Guangdong Province, China. 3. Department of Orthopaedics Surgery, Liuhuaqiao Hospital, Guangzhou 510010, Guangdong Province, China. Electronic address: gz_yqs@126.com.
Abstract
OBJECTIVES: This study aimed to compare the clinical efficacies of percutaneous endoscopic lumbar discectomy (PELD) and traditional open lumbar discectomy (OD). METHODS: The pre-operative and post-operative blood loss, hospital stays and wound sizes of the patients in the two groups were recorded. Enzyme-Linked immunosorbent assay was used to measure the changes of interleukin-6 (IL-6), C-reactive protein (CRP) and creatine phosphokinase (CPK) pre-operation and 1 h, 6 h, 12 h, 24 h and 48 h after corresponding surgery. Visual Analog Scale and Modified MacNab Criteria were used to assess post-operative results. RESULTS: Patients in the PELD group had less blood loss (p < 0.01), shorter hospitalization hours (p < 0.01) and smaller surgical wounds (p < 0.01) than the patients underwent traditional OD surgery. MacNab evaluated that the levels of satisfaction were above 90% in both groups post-operative six months. There was no significant difference in pain index between the two groups (p > 0.05). Furthermore, the levels of CRP, CPK and IL-6 in the PELD group were all lower than those in the OD group with a significant difference (p < 0.01). CONCLUSION: The PELD had less damage to human tissues than the traditional OD. PELD has a clear promotional value in clinical.
RCT Entities:
OBJECTIVES: This study aimed to compare the clinical efficacies of percutaneous endoscopic lumbar discectomy (PELD) and traditional open lumbar discectomy (OD). METHODS: The pre-operative and post-operative blood loss, hospital stays and wound sizes of the patients in the two groups were recorded. Enzyme-Linked immunosorbent assay was used to measure the changes of interleukin-6 (IL-6), C-reactive protein (CRP) and creatine phosphokinase (CPK) pre-operation and 1 h, 6 h, 12 h, 24 h and 48 h after corresponding surgery. Visual Analog Scale and Modified MacNab Criteria were used to assess post-operative results. RESULTS:Patients in the PELD group had less blood loss (p < 0.01), shorter hospitalization hours (p < 0.01) and smaller surgical wounds (p < 0.01) than the patients underwent traditional OD surgery. MacNab evaluated that the levels of satisfaction were above 90% in both groups post-operative six months. There was no significant difference in pain index between the two groups (p > 0.05). Furthermore, the levels of CRP, CPK and IL-6 in the PELD group were all lower than those in the OD group with a significant difference (p < 0.01). CONCLUSION: The PELD had less damage to human tissues than the traditional OD. PELD has a clear promotional value in clinical.