Literature DB >> 2458299

Alkali myosin light chains in man are encoded by a multigene family that includes the adult skeletal muscle, the embryonic or atrial, and nonsarcomeric isoforms.

U Seidel1, E Bober, B Winter, S Lenz, P Lohse, H W Goedde, K H Grzeschik, H H Arnold.   

Abstract

A set of cDNA clones coding for alkali myosin light chains (AMLC) was isolated from fetal human skeletal muscle. Nucleotide sequence analysis and RNA expression patterns of individual clones revealed related sequences corresponding to (i) fast fiber type MLC1 and MLC3; (ii) the embryonic MLC that is also expressed in fetal ventricle and adult atrium (MLCemb); and (iii) a nonsarcomeric MLC isoform that is found in all nonmuscle cell types and smooth muscle. The AMLC gene family in man comprises unique copies for MLC1, MLC3 and MLCemb, and multiple copies for the nonsarcomeric MLC genes. The gene coding for MLC1 and MLC3 is located on human chromosome 2.

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Year:  1988        PMID： 2458299     DOI： 10.1016/0378-1119(88)90231-4

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  9 in total

Review 1.  Myosin light chains and troponin C: structural and evolutionary relationships revealed by amino acid sequence comparisons.

Authors:  J H Collins
Journal:  J Muscle Res Cell Motil       Date:  1991-02       Impact factor: 2.698

2.  Modifier locus of the skeletal muscle involvement in Emery-Dreifuss muscular dystrophy.

Authors:  B Granger; L Gueneau; V Drouin-Garraud; V Pedergnana; F Gagnon; R Ben Yaou; S Tezenas du Montcel; G Bonne
Journal:  Hum Genet       Date:  2010-11-10       Impact factor: 4.132

3.  A novel isoform of myosin alkali light chain isolated from human muscle cells.

Authors:  K Zimmermann; A Starzinski-Powitz
Journal:  Nucleic Acids Res       Date:  1989-12-25       Impact factor: 16.971

4.  Differential expression of genes in cells cultured from juxtacanalicular trabecular meshwork and Schlemm's canal.

Authors:  E Timothy O'Brien; Yanhong Wang; Hongyu Ying; Beatrice Y J T Yue
Journal:  J Ocul Pharmacol Ther       Date:  2014-03-10       Impact factor: 2.671

Review 5.  Evolution of EF-hand calcium-modulated proteins. V. The genes encoding EF-hand proteins are not clustered in mammalian genomes.

Authors:  M W Berchtold
Journal:  J Mol Evol       Date:  1993-05       Impact factor: 2.395

6.  A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

Authors:  T Braun; G Buschhausen-Denker; E Bober; E Tannich; H H Arnold
Journal:  EMBO J       Date:  1989-03       Impact factor: 11.598

7.  Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.

Authors:  T Braun; E Bober; B Winter; N Rosenthal; H H Arnold
Journal:  EMBO J       Date:  1990-03       Impact factor: 11.598

8.  The genome of the giant Nomura's jellyfish sheds light on the early evolution of active predation.

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Journal:  BMC Biol       Date:  2019-03-29       Impact factor: 7.431

9.  Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences.

Authors:  Goran Bozinovic; Tim L Sit; Richard Di Giulio; Lauren F Wills; Marjorie F Oleksiak
Journal:  BMC Genomics       Date:  2013-11-11       Impact factor: 3.969
  9 in total

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