R Deniz Acar1, M Bulut2, S Ergün2, M Yesin2, G Alıcı2, M Akçakoyun2. 1. Kartal Kosuyolu Education and Research Hospital, Cardiology Department, Mevlanakapi Mah. Dingil Sok. No: 23/5, Sehremini/Fatih, Istanbul, Turkey. Electronic address: denizacar_1999@yahoo.com. 2. Kartal Kosuyolu Education and Research Hospital, Cardiology Department, Mevlanakapi Mah. Dingil Sok. No: 23/5, Sehremini/Fatih, Istanbul, Turkey.
Abstract
BACKGROUND: The objective of this study was to analyze the effects of cardiac rehabilitation (CR) on the atrial function of patients with acute myocardial infarction (AMI) who had been successfully revascularized through percutaneous coronary intervention (PCI). METHODS: Forty-two AMI patients having undergone CR were enrolled in this observational study. Assessments were performed before and after 6 weeks of CR. Left atrial strain analysis was carried out by two-dimensional speckle tracking echocardiography. Left ventricular ejection fraction (LVEF) was measured by the biplane Simpson's method. Pulsed-wave Doppler at the tip of mitral valve leaflets enabled us to measure early (E) and late (A) diastolic filling velocities, deceleration time (DT) of early filling velocity and isovolumic relaxation time (IVRT). Left ventricle tissue velocity was measured by tissue Doppler imaging of the lateral mitral annulus (e') and E/e' was subsequently calculated. Ratio of E/e' to left atrium (LA) peak strain was used to estimate LA stiffness. RESULTS: Following CR, LVEF (P=0.010), LA strain (P<0.001) and LA stiffness (P=0.013) all showed improvement, while other parameters remained unchanged. CONCLUSION: Post-AMI cardiac rehabilitation and revascularization by PCI might have favourable effects on LA function.
BACKGROUND: The objective of this study was to analyze the effects of cardiac rehabilitation (CR) on the atrial function of patients with acute myocardial infarction (AMI) who had been successfully revascularized through percutaneous coronary intervention (PCI). METHODS: Forty-two AMI patients having undergone CR were enrolled in this observational study. Assessments were performed before and after 6 weeks of CR. Left atrial strain analysis was carried out by two-dimensional speckle tracking echocardiography. Left ventricular ejection fraction (LVEF) was measured by the biplane Simpson's method. Pulsed-wave Doppler at the tip of mitral valve leaflets enabled us to measure early (E) and late (A) diastolic filling velocities, deceleration time (DT) of early filling velocity and isovolumic relaxation time (IVRT). Left ventricle tissue velocity was measured by tissue Doppler imaging of the lateral mitral annulus (e') and E/e' was subsequently calculated. Ratio of E/e' to left atrium (LA) peak strain was used to estimate LA stiffness. RESULTS: Following CR, LVEF (P=0.010), LA strain (P<0.001) and LA stiffness (P=0.013) all showed improvement, while other parameters remained unchanged. CONCLUSION: Post-AMI cardiac rehabilitation and revascularization by PCI might have favourable effects on LA function.
Authors: Antonello D'Andrea; Simona Sperlongano; Mario Pacileo; Elio Venturini; Gabriella Iannuzzo; Marco Gentile; Rossella Sperlongano; Giuseppe Vitale; Marco Maglione; Gennaro Cice; Filippo Maria Sarullo; Anna Di Lorenzo; Carlo Vigorito; Francesco Giallauria; Eugenio Picano Journal: J Clin Med Date: 2020-09-28 Impact factor: 4.964