Literature DB >> 2458269

Neuropeptide Y blocks a calcium current in C cells of bullfrog sympathetic ganglia.

G G Schofield1, S R Ikeda.   

Abstract

The effects of neuropeptide Y (NPY) on the Ca2+ current of enzymatically dispersed neuronal somata from bullfrog paravertebral sympathetic ganglia were investigated using the patch-clamp technique. In C neurons, NPY induced a concentration-dependent decrease in the amplitude of the Ca2+ current and induced a slow biphasic current rising phase. Upon removal of NPY these parameters returned to near control values. NPY had no discernable effect on the Ca2+ current recorded in B neurons.

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Year:  1988        PMID： 2458269     DOI： 10.1016/0014-2999(88)90702-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  8 in total

Review 1.  Neurotransmitter modulation of neuronal calcium channels.

Authors:  Keith S Elmslie
Journal:  J Bioenerg Biomembr       Date:  2003-12       Impact factor: 2.945

2.  Neuropeptides in hypertension: role of neuropeptide Y and calcitonin gene related peptide.

Authors:  T C Westfall; S P Han; M Knuepfer; J Martin; X L Chen; K del Valle; A Ciarleglio; L Naes
Journal:  Br J Clin Pharmacol       Date:  1990       Impact factor: 4.335

3.  Muscarinic modulation of calcium current in neurones from the interatrial septum of bull-frog heart.

Authors:  A Tse; R B Clark; W R Giles
Journal:  J Physiol       Date:  1990-08       Impact factor: 5.182

4.  Inhibition of nicotinic acetylcholine receptor channels in bovine adrenal chromaffin cells by Y3-type neuropeptide Y receptors via the adenylate cyclase/protein kinase A system.

Authors:  W Nörenberg; M Bek; N Limberger; K Takeda; P Illes
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-04       Impact factor: 3.000

5.  Investigations into neuropeptide Y-mediated presynaptic inhibition in cultured hippocampal neurones of the rat.

Authors:  D Bleakman; N L Harrison; W F Colmers; R J Miller
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

6.  Presynaptic inhibitory effects of the peptides NPY, PYY and PP on nicotinic EPSPs in guinea-pig gastric myenteric neurones.

Authors:  M Schemann; K Tamura
Journal:  J Physiol       Date:  1992       Impact factor: 5.182

7.  Melanostatin (NPY) inhibited electrical activity in frog melanotrophs through modulation of K+, Na+ and Ca2+ currents.

Authors:  J A Valentijn; H Vaudry; W Kloas; L Cazin
Journal:  J Physiol       Date:  1994-03-01       Impact factor: 5.182

8.  Neuropeptide Y inhibits nicotinic cholinergic currents but not voltage-dependent calcium currents in bovine chromaffin cells.

Authors:  W Nörenberg; P Illes; K Takeda
Journal:  Pflugers Arch       Date:  1991-05       Impact factor: 3.657
  8 in total

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