Lilliam Flores1, Josep Vidal2, Silvia Canivell3, Salvadora Delgado4, Antonio Lacy4, Enric Esmatjes5. 1. Obesity Unit, Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain; CIBERDEM: Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Barcelona, Spain. Electronic address: lflores@clinic.ub.es. 2. Obesity Unit, Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain; CIBERDEM: Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain. 3. CIBERDEM: Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain. 4. Department of Gastrointestinal Surgery, Hospital Clinic, Barcelona, Spain. 5. CIBERDEM: Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain; Diabetes Unit, Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain.
Abstract
BACKGROUND: There is scarce information about predictive factors of hypertension (HT) remission after bariatric surgery (BS). The aims of this study were to determine the clinical characteristics differentiating obese patients with and without HT and to evaluate the predictive factors associated with the risk of persistence of HT after BS. PATIENTS AND METHODS: From January 2007 to December 2009, a review of patients who had undergone BS was performed. Patients were classified as hypertensive if having permanent use of antiHT drugs or clinical BP ≥ 140/90 mm Hg. Weight, waist circumference (WC), and blood pressure were determined with standardized procedures. RESULTS: Five hundred twenty-6 patients met the inclusion criteria; 264 (50%) were hypertensive, 74 (34%) of whom had type 2 diabetes. Before BS, older age, male gender, and greater WC differentiated hypertensive from normotensive patients. The prevalence of HT significantly fell to 35% (P<.0001) at 12 months after BS. The use of multivariate logistic regression showed that age ≥ 40, male gender and WC ≥ 130 cm were significant predictors of having HT before surgery. Regarding persistence of HT at the 12-month follow-up, the only independent predictors observed were time since diagnosis of HT ≥ 10 years and the number of antiHT drugs used. Presurgical BMI, WC, excess weight (EW), EW loss, surgical procedure, type 2 diabetes, and vitamin D status were not significant predictors. CONCLUSIONS: Bariatric surgery is associated with a high rate of HT remission. Older age, male gender, and higher WC differentiated hypertensive-obese from normotensive patients. After BS, longer duration and severity of HT were independently associated with no remission of HT.
BACKGROUND: There is scarce information about predictive factors of hypertension (HT) remission after bariatric surgery (BS). The aims of this study were to determine the clinical characteristics differentiating obesepatients with and without HT and to evaluate the predictive factors associated with the risk of persistence of HT after BS. PATIENTS AND METHODS: From January 2007 to December 2009, a review of patients who had undergone BS was performed. Patients were classified as hypertensive if having permanent use of antiHT drugs or clinical BP ≥ 140/90 mm Hg. Weight, waist circumference (WC), and blood pressure were determined with standardized procedures. RESULTS: Five hundred twenty-6 patients met the inclusion criteria; 264 (50%) were hypertensive, 74 (34%) of whom had type 2 diabetes. Before BS, older age, male gender, and greater WC differentiated hypertensive from normotensive patients. The prevalence of HT significantly fell to 35% (P<.0001) at 12 months after BS. The use of multivariate logistic regression showed that age ≥ 40, male gender and WC ≥ 130 cm were significant predictors of having HT before surgery. Regarding persistence of HT at the 12-month follow-up, the only independent predictors observed were time since diagnosis of HT ≥ 10 years and the number of antiHT drugs used. Presurgical BMI, WC, excess weight (EW), EW loss, surgical procedure, type 2 diabetes, and vitamin D status were not significant predictors. CONCLUSIONS: Bariatric surgery is associated with a high rate of HT remission. Older age, male gender, and higher WC differentiated hypertensive-obese from normotensive patients. After BS, longer duration and severity of HT were independently associated with no remission of HT.
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